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Table 2 Included studies table

From: Psychotherapies for eating disorders: findings from a rapid review

#

Author, year

Country

Nparticipants

Nstudies

Population

Aim

Design

Outcome measure

1

Aardoom et al., 2013 [19]

Worldwide

 

21

Mixed (mixed cohort, Both sexes)

To review the literature regarding internet-based treatment of EDs

Review (systematic)

ED psychopathology, frequency of binge eating and purging, improving (ED-related) quality of life

2

Accurso et al., 2014 [20]

USA

121

 

Outpatient (adolescent, both sexes)

To describe change in psychological outcomes for adolescents with AN, and to explore predictors of change

RCT

Severity of eating disorder pathology using the EDE V12.0; depressive symptoms using the BECK Depression Inventory (BDI) and body weight

3

Accurso et al., 2015 [21]

USA

80

 

Community (Adult, Both sexes)

To examine the temporal relation between therapeutic alliance and outcome in two treatments for BN

RCT

Temporal relation between therapeutic alliance and outcome

4

Agras et al., 2014 [22]

USA

164

 

Outpatient (adolescent, both sexes)

To compare FBT with systemic family therapy for the treatment of adolescent-onset anorexia nervosa

RCT

Percentage of ideal body weight and remission (≥ 95% of ideal body weight)

5

Agras, Fitzsimmons-Craft and Wilfley, 2017 [23]

N/A

 

N/A

Mixed (mixed cohort, both sexes)

To describe the evolution of CBT for the treatment of bulimic disorders

Review (Narrative)

Varied

6

Aguera et al., 2013 [24]

Spain

454

 

Outpatient (adult, females)

To determine differences in treatment response and dropout rates following CBT across the three bulimic-spectrum syndromes

Repeated measures (without follow up)

Full remission defined as total absence of bingeing and purging behaviours and psychological improvement for at least 4 (consecutive)

7

Aguera et al., 2017 [25]

Spain

262

 

Outpatient (adult, both sexes)

To compare treatment outcomes and clinical predictors between men and women with EDs

Cross-sectional

Clinical predictors of treatment outcome—ED severity, personality and psychopathology

8

Ahmadiankalati, Steins-Loeber and Paslakis, 2020 [26]

N/A

 

12

Outpatient (mixed cohort, both sexes)

To identify and analyse the current evidence of RCTs to evaluate the effectiveness and acceptability of e-health interventions in the ED field

Review (other)

Acceptability, effectiveness of effect on eating behaviour

9

Alfonsson, Parling and Ghaderi, 2015 [27]

Sweden

96

 

Inpatient (undefined)

To assess whether behavioural activation is an efficacious treatment for decreasing ED symptoms in patients with obesity and BED

RCT

Frequency of binge-eating; depressive symptoms and mood

10

Anastasiadou et al., 2020 [28]

Spain

106

 

Outpatient (mixed cohort, both sexes)

To assess the clinical efficacy of a combined mHealth intervention for EDs based on CBT

RCT

ED symptomatology, anxiety, depression and quality of life

11

Anderson et al., 2020 [29]

USA

112

 

Outpatient (adult, both sexes)

To examine predictors and moderators of two interventions for binge-eating disorder

RCT

Frequency of Objective Binge-eating Episode (OBE) and OBE-abstinence at end-of-treatment (EOT) and 6-month follow up

12

Ariel and Perri, 2016 [30]

USA

572

 

Outpatient (adult, both sexes)

To evaluate the effects of a behavioural intervention for obesity compared with a nutrition education group on binge eating

RCT

Binge-eating severity using the Binge Eating Scale and weight status, weight status at base line and 6 months and treatment adherence over 6 months

13

Austin et al., 2022 [31]

UK

502

 

Outpatient (young people, both sexes)

To assess the scalability of First Episode Rapid Early Intervention for ED service model and care pathway

Quasi-experimental (intervention)

Eating Disorder Examination Questionnaire (EDE-Q), Clinical Outcomes in Routine Evaluation, Clinical Impairment Assessment (CIA), The Depression, Anxiety, and Stress Scale—21 items (DASS-21), Work and Social Adjustment Scale (WSAS), Levels of Expressed Emotion Scale (LEE), Psychological Outcome Profiles (PSYCHLOPS), Body mass index

14

Bankoff et al., 2012 [32]

Worldwide

 

13

Outpatient (mixed cohort, both sexes)

To conduct a literature review to locate referred articles testing dialectical behaviour therapy for the treatment of EDs

Review (systematic)

Treatment efficacy on ED behaviours and other forms of psychopathology

15

Baudinet et al., 2021 [10]

Worldwide

 

27

Mixed (mixed cohort, both sexes)

To review the quantitative and qualitative evidence-base for multi-family therapy (MFT) for eating disorders regarding change in physical and psychological symptoms, broader individual and family factors, and the experience of treatment

Review (systematic scoping)

Global outcomes, weight, ED psychopathology, and mood

16

Bauer et al., 2012 [33]

Germany

165

 

Inpatient (adult, females)

To examine the efficacy of a program delivered via the short message service (SMS) and text messaging in support patients after their discharge from inpatient treatment

RCT

Rate of partial remission, 8 months after discharge

17

Beintner, Jacobi and Schmidt, 2014 [34]

Worldwide

 

73

Outpatient (mixed cohort, both sexes)

To review and analyse participation and outcome in manualized self-help for BN and BED

Systematic review/meta-analysis (combined)

Varied

18

Bentz et al. 2021 [35]

Denmark

157

 

Outpatient (young people, both sexes)

To evaluate outcomes of FBT for restrictive-type eating disorders, delivered as standard care in a public mental health service

Quasi-experimental (Intervention)

Remission, frequency of hospital admissions and day-patient treatment, frequency of other adaptations within 12 months from commencement of treatment

19

Berking et al. 2022 [36]

Germany

101

 

Community (adult, both sexes)

To test whether systematically enhancing emotion regulation skills would reduce symptoms of BED

RCT

Binge-eating symptoms, emotion regulation skills

20

Blanchet et al., 2018 [37]

Worldwide

 

8

Outpatient (adult, both sexes)

To assess the evidence regarding the role of physical activity in BED and to better understand the mechanisms of action

Review (systematic)

Binge-eating episode frequency; changes in other associated comorbidities

21

Boerhaut et al., 2016 [38]

The Netherlands

40

 

Outpatient (adult, females)

To evaluate the effect of a brief body and movement-oriented intervention on aggression regulation and ED pathology for individuals with ED’s

RCT

Aggression regulation and ED pathology

22

Boerhaut et al., 2017 [39]

The Netherlands

70

 

Outpatient (adult, both sexes)

To evaluate a body and movement-oriented intervention on aggression regulation, aimed towards reducing anger internalization in patients with an ED

RCT

Aggression regulation

23

Bourion-Bedes et al., 2013

France

108

 

Inpatient (young people, both sexes)

To determine whether patients’ perception of early therapeutic alliance could predict time to achieve a target weight

Repeated Measure (without follow-up)

Time to achieve a target weight

24

Brauhardt, de Zwaan and Hilbert, 2014 [40]

Worldwide

 

123?

Community (mixed cohort, both sexes)

To investigate the evidence supporting the impact of therapeutic process aspects on outcomes

Review (systematic)

The impact of therapeutic process aspects on outcome (i.e., process-outcome research)

25

Brewin et al., 2016 [41]

UK

158

 

Mixed (mixed cohort, both sexes)

To evaluate the effect of a newly developed motivational and psycho-educational guided self-help intervention for people with ED’s on engagement and retention in therapy

Repeated Measures (without Follow Up)

Rates of engagement and completion of therapy

26

Brockmeyer et al., 2019 [42]

Germany

56

 

Outpatient (adult, both sexes)

To examine if approach bias modification reduces approach-basis automatic action tendencies toward food and may decrease BE and related symptoms

RCT

Number of objective binge-eating episodes (OBEs) as assessed by the Eating Disorder Examination (EDE) and ED symptoms

27

Brockmeyer, Friederich and Schmidt, 2018 [43]

Worldwide

 

19

Community (adolescent, both sexes)

To synthesise evidence on established and emerging anorexia nervosa treatments and to forecast future development trends

Review (systematic)

Outcomes of clinical trials on established AN treatment

28

Brockmeyer et al., 2021 [44]

Germany

167

 

Community (adult, both sexes)

To evaluate potential treatment-enhancing effects of CRT on cognitive and clinical outcomes in a large sample of patients with AN in a randomized controlled trial with equal treatment dosage in the comparator condition

RCT

BMI, ED psychopathology, health-related quality of life, motivation to change, set-shifting, central coherence

29

Brown, Mountford, and Waller, 2013 [45]

UK

65

 

Outpatient (adult, both sexes)

To establish the strength of the therapeutic alliance (TA), to determine if early TA is associated with the completion of CBT and the direction of the relationship between TA and weight gain

Longitudinal (< 5 years)

Weight gain (BMI change), Working Alliance Inventory (WAI-SR), Eating Disorders Examination (EDE-Q)

30

Brownley et al., 2016 [46]

Worldwide

 

34

Outpatient (adult, both sexes)

To summarise evidence about the benefits and harms of psychological and pharmacologic therapies for adults with BED

Systematic review/meta-analysis (combined)

Abstinence from binge-eating, binge-eating frequency, eating-related psychotherapy symptoms of depression, body weight

31

Butler and Heimberg, 2020 [47]

Worldwide

 

60

Inpatient and outpatient (mixed cohort, both sexes)

To review the literature on exposure interventions for EDs; exposure and response prevention, in vivo feared food exposure, mirror exposure, FBT with exposure, and virtual reality exposure therapy

Review (systematic)

Testing anxiety levels, calorie intake, BMI

32

Buerger et al., 2021 [48]

Worldwide

487

19

Mixed (young people, both sexes)

To estimate the efficacy of third-wave interventions to reduce ED symptoms in adolescents in randomized controlled trials (RCTs) and uncontrolled studies

Systematic review/meta-analysis (combined)

ED psychopathology (EDE, EDEQ, Eating Disorder Inventory-2, Eating Disorder Inventory-3, Structured Interview for Anorexic and Bulimic Disorders for DSM-IV and ICD-10)

33

Byrne et al., 2011 [49]

Australia

125

 

Community (adult, both sexes)

To examine the effectiveness of Enhanced Cognitive Behaviour Therapy (CBT-E) for EDs in an open trial for adults with the full range of EDs found in the community

Quasi-experimental (intervention)

Categorical measures of recovery, dimensional measures of change in the severity of ED features, compensatory behaviours, dietary restraint, eating, weight and shape concerns, measures of additional variables specified in the transdiagnostic model, and measures of other associated psychopathology

34

Calugi et al. 2021 [50]

Italy

214

 

Inpatient (mixed cohort, both sexes)

To compare the change in eating-disorder feature networks in patients with anorexia nervosa after treatment with intensive enhanced cognitive behaviour therapy (CBT-E)

Quasi-experimental (intervention)

BMI, EDEQ

35

Cardi et al., 2020 [51]

UK

187

 

Outpatient (adult, both sexes)

To examine if adding a brief online intervention focused on enhancing motivation to change and the development of a recovery identity would improve outcomes in adults with AN

RCT

Body Mass Index, frequency of eating disorder symptoms, psychological wellbeing and work and special adjustment and anxiety

36

Carrard et al., 2011 [52]

Switzerland

127

 

Community (adult, females)

To evaluate the use of an online guided self-treatment programme for BN and to determine predictors of outcome

Quasi-experimental (intervention)

Eating Disorders Inventory-2 (EDI-2) and The Symptom Checklist-revised (SCL-90R)

37

Carrard et al., 2011 [53]

Switzerland

74

 

Community (adult, females)

To evaluate the efficacy of an internet guided self-help treatment programme, based on CBT, for adults with threshold and subthreshold BED

RCT

Number of objective binge-eating episodes (OBEs) as assessed by the Eating Disorder Examination (EDE-Q) and ED symptoms score (EDI-2), perceived hunger, psychological health, depression, self-esteem and quality of life

38

Catalan-Matamoros et al., 2011 [54]

Spain

28

 

Outpatient (adult, both sexes)

To analyse the feasibility of Basic Body Awareness Therapy in people with EDs

RCT

Eating Disorder Inventory, Eating Attitude Test, Body Attitude Test and Quality of Life Scale (SF-36)

39

Cesa et al., 2013 [55]

Italy

90

 

Outpatient/inpatient (adult, females)

To test the brief and long-term clinical efficacy of an enhanced CBT in morbidly obese patients with BE disorders compared with standard CBT

RCT

Weight loss, weight loss maintenance, BED remission, body-satisfaction improvement

40

Chami et al., 2022 [56]

UK

78

 

Community (adult, both sexes)

To examine the feasibility, acceptability, and effect sizes of clinical outcomes of an intervention that combines inhibitory control training (ICT) and implementation intentions (if–then planning) to target binge eating and eating disorder psychopathology

RCT

ED psychopathology (EDE-Q), weight, self-regulation of eating, food valuation, food approach, depression and anxiety

41

Chang, Delgadillo and Waller, 2021 [57]

Worldwide

 

26

Outpatient (mixed cohort, both sexes)

To examine literature that states that early response is a well-established predictor of positive outcomes at the end of psychological treatments for common mental disorders

Systematic Review/Meta-Analysis (Combined)

The statistical significance and magnitude of the association between early response to ED treatment and outcomes

42

Chen et al., 2017 [58]

USA

109

 

Outpatient (adult, females)

To improve the outcome of clients with weak initial response to guided self-help CBT

RCT

Frequency of and abstinence from ED behaviour and psychopathology using the EDE

43

Ciao et al., 2015 [59]

USA

80

 

Outpatient (adolescent, both sexes)

To examine predictors of psychological change among adolescents with BN comparing FBT to supportive psychotherapy

RCT

Abstinence from bingeing and purging; psychological outcomes (cognitive ED pathology (i.e., Shape/Weight Concerns, Eating Concerns, and Restraint), depression, and self-esteem

44

Clyne et al., 2010 [60]

New Zealand

23

 

Outpatient (adult, females)

To examine the efficacy of a treatment for BED designed to increase recognition and regulation of negative emotion, replicating and extending a previous investigation

Repeated measures (with follow up)

Binge-abstinence rates, pre and post study treatment effects

45

Compare and Tasca, 2016 [61]

Italy

118

 

Outpatient (adult, both sexes)

To investigate the change and relationship between BE episodes and weight across focused group therapy and combined therapy of EFGT plus dietary counselling for BED

Longitudinal (< 5 years)

Binge-eating episodes and body weight

46

Compare et al., 2013 [62]

Italy

189

 

Outpatient (adult, both sexes)

To test the effect on psychopathology and QOL of Emotionally Focused Therapy, Dietary Counselling, and Combined Treatment in patients with BED and obesity

Longitudinal (< 5 years)

Health-related quality of life, using ORWELL-97; attitudes toward eating (Eating Inventory—EI), binge eating (Binge Eating Scale—BES) and body uneasiness (Body Uneasiness Test—BUT) was performed at baseline, end-of-treatment, and 6-month follow-up

47

Coomber and King, 2012 [63]

Australia

56

 

Community (mixed cohort, both sexes)

To examine predictors of both carer burden and carer psychological distress in ED carers

Cross-sectional

Eating Disorders Symptom Impact Scale (EDSIS), Carers’ Needs Assessment Measure (CaNAM), General Health Questionnaire-12 (GHQ-12), Brief COPE, Social Support Questionnaire (SSQ6), Family Questionnaire (FQ)

48

Coomber and King, 2013 [64]

Australia

42

 

Community (adult, both sexes)

To conduct a preliminary longitudinal examination of the predictors of carer burden and psychological distress for carers of those with an ED

Longitudinal (< 5 years)

Eating Disorders Symptom Impact Scale (EDSIS), Carers’ Needs Assessment Measure (CaNAM), General Health Questionnaire-12 (GHQ-12), Brief COPE, Social Support Questionnaire-Short Form (SSQ6), Family Questionnaire (FQ)

49

Costa and Melnik, 2016 [65]

Worldwide

 

N/A

Community (mixed cohort, both sexes)

To compile findings of relevant scientific papers, such as randomized controlled trials, systematic reviews, meta-analysis, guidelines and narrative reviews of literature, in order to promote knowledge about effectiveness of psychosocial interventions in EDs along time, in addition to showing the need for further research in specific areas

Review (narrative)

Symptomatic remission; for AN- BMI; for BN-100% withdrawal from binge eating, bulimic symptoms; for BED/eating disorder not otherwise specified (EDNOS)-remission of bulimic symptoms, weight BMI

50

Courbasson, Nishikawa and Shapira, 2010 [66]

Canada

38

 

Mixed (mixed cohort, both sexes)

To examine treatment outcome for individuals with BED and those who often evidenced comorbid substance use disorders

Repeated measures (without follow up)

Measures of objective binge-eating episodes; disordered eating attitudes; alcohol and drug addiction severity; depression

51

Couturier, Kimber and Szatmari, 2012 [67]

Worldwide

 

6

Outpatient (adolescent, both sexes)

To review and evaluate the efficacy of FBT compared with individual treatment among adolescents with EDs

Systematic review/meta-analysis (combined)

Remission rate at end of treatment, 6 and 12 month follow up

52

Craig et al., 2019 [68]

UK

54

 

Community (adolescent, both sexes)

To consider the effectiveness of CBT for EDs where family-based treatment was either not fully effective or not applicable

Case series

Eating attitudes and clinical impairment, and weight change

53

Dakanalis et al., 2014 [69]

Italy

679

 

Outpatient (adult, both sexes)

To evaluate and compare the original cognitive-behavioural model and the enhanced cognitive-behavioural model

Cross-sectional (correlational)

Diagnosis of ED

54

Dalle Grave et al., 2015 [70]

Worldwide

 

68

Outpatient (adolescent, both sexes)

To evaluate the effects of CBT on non-underweight adolescents with an ED

Review (systematic)

Body weight and BMI; Eating Disorder features using EDE-Q6.0; general psychiatric features from Global Severity Index (GSI)

55

Daniel, Poulsen and Lunn, 2016 [71]

Denmark

70

 

Community (adult, females)

To perform secondary analyses on the relation between attachment and pre-treatment symptom levels

Repeated measure (with follow-up)

Attachment and pre-treatment symptom levels, pre-treatment attachment treatment outcome moderation, change in client attachment associated with symptomatic change, changes to client attachment

56

Daniel, Lunn and Poulsen, 2015 [72]

Denmark

70

 

Outpatient (adult, both sexes)

To perform analyses of the relation between attachment and pre-treatment symptom levels for BN with respect to outcome, symptoms and client attachment

RCT

Moderation/change in assessment at intake included Eating Disorder Examination (EDE), Adult Attachment Interview, Symptom Checklist 90-R

57

de Jong, Schoorl and Hoek, 2018 [73]

Worldwide

 

7

Outpatient (adult, both sexes)

To provide an update of CBT-E effectiveness studies on BN, BED and transdiagnostic samples

Review (systematic)

Post treatment remission rates

58

de Zwaan et al., 2017 [74]

Germany

178

 

Outpatient (adult, both sexes)

To evaluate the efficacy of internet-based guided self-help compared with traditional, individual face-to-face CBT

RCT

Difference in number of days with objective binge-eating episodes (OBEs) during the previous 28-days between baseline and treatment; OBEs at follow ups, ED and general psychopathologic findings, body mass index, and quality of life

59

Diaz-Ferrer et al., 2015 [75]

Spain

29

 

Outpatient (adult, females)

To compare the efficacy of two body exposure techniques through psychological and neuroendocrine indices within and between successive sessions

RCT

Body satisfaction and changes in subjective discomfort

60

Dolemeyer et al., 2013 [76]

Worldwide

 

8

Mixed (mixed cohort, both sexes)

To evaluate the efficacy of internet-based interventions for the treatment of different EDs in adults

Review (systematic)

Varied

61

Dray and Wade, 2012 [77]

Worldwide

 

9

Community (mixed cohort, both sexes)

To examine the utility of the transtheoretical model and the efficacy of motivational interviewing in predicting outcome of research in EDs

Review (critical)

Utility of the transtheoretical model in predicting outcome, and efficacy of motivational interviewing

62

Egger et al., 2016 [78]

Germany

156

 

Outpatient (adult, females)

To determine the cost-effectiveness of outpatient focal psychodynamic psychotherapy, CBT-E, and optimized TAU in adult women with AN

RCT

Cost effectiveness

63

Eisler et al., 2016 [79]

UK

169

 

Outpatient (adolescent, both sexes)

To compare two outpatient ED focussed family interventions; multi-family therapy and single family therapy

RCT

Achieving good or intermediate outcome on the Morgan-Russell scales at the end of treatment

64

Ertelt et al., 2011 [80]

N/A

 

116?

Outpatient (adult, females)

To examine ratings of therapeutic alliance factors in telemedicine and face-to-face CBT

Review (narrative)

Working Alliance Inventory (WAI) completed by patients and therapists at weeks 2, 8, and 16

65

Fairburn et al., 2009 [18]

UK

154

 

Outpatient (adult, both sexes)

To compare two cognitive-behavioural treatments for outpatients with EDs

RCT

ED features and mood intolerance, clinical perfectionism, low self-esteem, or interpersonal difficulties

66

Fairburn et al., 2013 [81]

UK

99

 

Outpatient (adult, both sexes)

To establish the immediate and longer-term outcome following CBT-E

Repeated Measure (with follow-up)

BMI, ED features and psychiatric features

67

Fairburn et al., 2015 [82]

UK

130

 

Outpatient (adult, both sexes)

To compare CBT with interpersonal psychotherapy

RCT

ED features and remission rate using the Eating Disorder Examination Interview (EDE and EDE-Q6.0)

68

Fernandez-Aranda et al., 2015 [83]

Spain

38

 

N/A

To compare outcomes of outpatient CBT + serious video game (SVG), with outpatient CBT—SVG, and effect in reducing emotional expression and levels of anxiety than CBT—SVG

Control Trial

Drop-out, partial remission, and total remission

69

Ferrer-Garcia and Gutierrez-Maldonado, 2012 [84]

N/A

 

N/A

Mixed (Mixed cohort, both sexes)

To review research of virtual reality in the study, assessment, and treatment of body image disturbances in EDs and nonclinical samples

Review (narrative)

N/A

70

Ferrer-Garcia et al., 2019 [85]

N/A

 

58

Outpatient (adult, both sexes)

To assess the 6-month follow up of virtual reality cue exposure therapy as a second-level treatment for BN patients and binge ED following CBT

Review (narrative)

Frequency of binge-eating episodes and purging using the ED Examination Interview 12.0D

71

Ferrer-Garcia et al., 2017 [86]

Spain

64

 

Outpatient (adult, both sexes)

To assess virtual reality cue exposure therapy as a second-level treatment for BN patients and binge eating disorder following CBT

RCT

Frequency of binge-eating episodes and purging using the ED Examination Interview 12.0D

72

Fioravanti et al., 2014 [87]

Italy

102

 

Community (adult, females)

To evaluate whether the emotional eating profile of ED patients changes over time and the effects of psychotherapeutic intervention

Repeated Measure (without follow-up)

Emotional eating

73

Fisher et al., 2019 [88]

Australia

 

25

Outpatient (mixed cohort, both sexes)

To evaluate the efficacy of family therapy approaches compared with standard treatment and other treatments for AN

Review (other)

Remission post intervention, remission long-term follow up, and mortality at long-term follow up

74

Fitzsimmons-Craft et al., 2020 [89]

USA

690

 

Outpatient (adult, females)

To determine whether a coached, digital, CBT intervention improves outcomes for college women with EDs compared with referral to usual care

RCT (cluster)

Changes in overall ED psychopathology, binge eating and compensatory behaviours, ED behaviour frequencies, depression, anxiety, clinical impairment, academic impairment and realised treatment access

75

Fitzsimmons-Craft et al., 2023 [90]

USA

90

 

Mixed (adult, females)

To estimate the preliminary feasibility and effectiveness of a CBT-based mobile intervention plus treatment as usual (TAU), offered with and without an accompanying social networking feature

RCT

Feasibility, ED psychopathology, frequency of ED behaviours, anxiety, depression and suicidal ideation, clinical impairment, BMI, dietary restraint, weight/shape concern, AN Stages of Change Questionnaire, social support, duration of illness

76

Fogarty, Ramjan and Hay, 2016 [91]

Worldwide

 

4

N/A

To explore the benefits, effects and experiences of mentoring on those with an ED or disordered eating

Systematic review/meta-analysis (combined)

Varied

77

Folke, Daniel and Poulsen, Lunn 2016 [92]

Denmark

70

 

Community (adult, both sexes)

To investigate the relation between clients’ attachment patterns and the therapeutic alliance in two psychotherapies for BN

RCT

Client attachment patterns and therapeutic alliance

78

Fox, Dean and Whittlesea, 2015 [93]

Worldwide

 

20

Mixed (mixed cohort, both sexes)

To establish the acceptability, feasibility and approximate size of the effect of adding a carer intervention to treatment as usual for adolescents with AN

Systematic review/meta-analysis (combined)

Impact upon family members, cognitive appraisals and caregiving experience

79

Gan et al., 2021 [94]

Worldwide

 

19

Mixed (mixed cohort, both sexes)

To synthesize the best available evidence regarding the effectiveness of non-pharmacological interventions on body mass index (BMI), body dissatisfaction, depression and anxiety among individuals with anorexia nervosa (AN)

Systematic review/meta-analysis (combined)

BMI, body dissatisfaction, depression, anxiety

80

Gale, Gilbert and Goss, 2014 [95]

UK

99

 

Outpatient (adult, both sexes)

To evaluate the principle that compassion focused therapy can be used with people with EDs and can improve symptomatology

Repeated measure (without follow-up)

Compassion focused therapy outcomes for people with EDs

81

Gallagher et al., 2014 [96]

Canada

102

 

Outpatient (adults, females)

To conceptualise interpersonal learning as the convergence over time between an individual’s and the group’s perception of the individual’s cohesion to the group

Repeated measures (without follow up)

Cohesion questionnaire—individual version (CQ-1) score and Cohesion to the Group (CQ-G) rating, administered every fourth-group session

82

Garrett et al., 2014 [97]

USA

21

 

Outpatient (adult, females)

To investigate brain activation and set-shifting and central coherence tasks in patients with AN

Repeated measure (with follow-up)

Central coherence and set shifting

83

Godart et al., 2022 [98]

France

60

 

(Young people, females)

To present the results of a 54-month post-randomization follow-up of a previously reported randomized controlled trial that compared two post-hospitalization outpatient treatment programs: Treatment As Usual alone versus Systemic Family Therapy added to Treatment As Usual

RCT

Morgan and Russell global outcome categories, Global Outcome Assessment Schedule score, BMI, amenorrhea, number of hospitalisations, ED symptoms

84

Gomez-Castillo et al., 2018 [99]

Spain

348

 

Outpatient (mixed cohort, both sexes)

To examine the differences in ED symptoms in parents and their children as patients with AN, bulimia nervosa, unspecified ED and a control group

Case series

ED symptoms as measured on the Eating Disorder Inventory (EDI)

85

Gorrell, Loeb and Le Grange, 2019 [100]

N/A

 

N/A

Outpatient (adolescents, both sexes)

To describe the role of family engagement within FBT of EDs and the interventions

Review (narrative)

Not defined

86

Graham and Walton, 2011 [101]

UK

40

 

Outpatient (adult, both sexes)

To offer CD-Rom CBT self-help treatment, in a locality-based outpatient NHS ED Service to patients who have BE disorder and BN

Cross-sectional

Wellbeing and functioning, problems and risk; Bulimic Sub Scale of the Eating Disorder Index; dropout rate

87

Gregertsen et al., 2019 [102]

Worldwide

 

27

Outpatient (mixed cohort, both sexes)

To summarise the evidence base examining baseline predictors of drop-out and outcome in anorexia nervosa treatment

Systematic review/meta-analysis (combined)

Baseline predictors of drop-out rate

88

Grenon et al., 2017 [103]

Canada

 

27

Outpatient (adults, both sexes)

To review the effect of group psychotherapy compared to both wait-list controls and other active treatments for adults with ED’s

Meta-analysis

Abstinence rates of binge-eating and/or purging; ED psychopathology

89

Griffen, Naumann and Hilderbrant, 2018 [104]

N/A

 

N/A

Outpatient (mixed cohort, both sexes)

To discuss how individuals respond when looking in a mirror and the use of mirrors therapeutically; to evaluate the benefits, clinical indications and technical considerations for the use of mirror exposure therapy

Review (narrative)

Varied

90

Griffiths et al., 2015 [105]

Australia

317

 

Community (mixed cohort, both sexes)

To examine the prevalence and correlates of stigma as reported by individuals with EDs

Cross-sectional

Stigma Scale, Self-Stigma of Seeking Help scale (SSOSH), Depression Anxiety Stress Scales (DASS-21), Self-Esteem Scale (SES), Eating Disorder Examination Questionnaire (EDE-Q)

91

Griffiths et al., 2018 [106]

Australia

425

 

Outpatient (adults, both sexes)

To quantitatively examine individuals’ attitudes towards accessing treatment and perceived barriers to seeking treatment for EDs

Case series

Treatment attitudes, treatment barriers, and eating disorder symptom severity

92

Grilo et al., 2011 [107]

USA

125

 

Outpatient (adults, both sexes)

To compare CBT, Behaviour Weight Loss (BWL), and sequential approach in which CBT is delivered first followed by BWL (CBT + BWL)

RCT

Binge-eating remission rates and BMI losses

93

Grilo et al., 2013 [108]

USA

48

 

Outpatient (mixed cohort, both sexes)

To examine the effectiveness of a self-help treatment as a first line primary care intervention for BED in obese patients

RCT

Rates of remission of binge-eating; frequency of objective bulimic episodes using the Eating Disorder Examination Interview (EDE); depression using BDI

94

Grilo et al., 2020 [109]

USA

191

 

Community (adult, both sexes)

To examine longer-term effects of behavioural weight loss and Stepped Care for BED and obesity through 12-month follow-up after completing treatments

RCT

Frequency of Binge-eating, body weight

95

Groff, 2015 [110]

N/A

 

6

Community (adult, both sexes)

To review the current empirical research regarding CBT-E in the treatment of EDs

Review (other)

Effectiveness of enhanced cognitive behavioural therapy (CBT-E)

96

Grover et al., 2011 [111]

UK

64

 

Community (mixed cohort, both sexes)

To evaluate the efficacy of a novel web-based systemic cognitive-behavioural intervention for carers of people with AN

RCT

Depression and anxiety; expressed emotion (EE)

97

Grover et al., 2011 [112]

UK

 

27

Community (adult, both sexes)

To evaluate the feasibility and acceptability of a novel systemic CBT intervention for carers of people with anorexia nervosa (AN)

Review (other)

Hospital Anxiety and Depression Scale (HADS), Experience of Care Giving Inventory (ECI), The Eating Disorder Symptom Impact Scale (EDSIS)

98

Hay and Claudino, 2015 [113]

Worldwide

 

8

Mixed (mixed cohort, both sexes)

To conduct a review on the effects of online interventions for people with BN

Review (systematic)

Varied

99

Hay et al., 2009 [114]

Worldwide

3054

48

Outpatient (adult, both sexes)

To evaluate the efficacy of CBT, CBT-BN and other psychotherapies

Review (systematic)

Efficacy of CBT, CBT‐BN and other psychotherapies

100

Hay et al., 2022 [115]

Australia

98

 

Outpatient (adults, both sexes)

To explore the efficacy of a novel intervention integrating Cognitive Behavioural Therapy- Enhanced (CBT-E) and weight management for people with recurrent binge eating episodes and high BMI with respect to physical, psychopathological and quality of life outcomes

RCT

Metabolic parameters, health-related quality of life, general psychological and ED symptoms, ED diagnostic status outcomes

101

Hay, Touyz, and Sud, 2012 [116]

Worldwide

 

N/A?

Mixed (mixed cohort, both sexes)

To conduct a review of RCTs of treatment for chronic AN participants and identify research informing novel therapeutic approaches

Review (systematic)

Efficacy of treatment

102

Haynos et al., 2017 [117]

USA

80

 

Outpatient (adult, both sexes)

To use statistical analyses to identify ED subtypes within individuals with BN and to predict clinical outcomes

RCT

Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ), Eating Disorder Examination (EDE)

103

Hazzard et al., 2021 [118]

USA

112

 

Community (adults, both sexes)

To examine childhood abuse and post‐traumatic stress disorder (PTSD) as predictors and moderators of binge‐eating disorder (BED) treatment outcomes in a randomized controlled trial comparing Integrative Cognitive‐Affective Therapy with cognitive‐behavioural therapy administered using guided self‐help

RCT

Binge-eating frequency, EDE

104

Herbrich-Bowe et al., 2022 [119]

Germany

56

 

Inpatient (young people, females)

To compare CRT with non‐specific cognitive training (NSCT) on set‐shifting and central coherence ability as well as self‐reported everyday life flexibility in the first RCT in adolescent inpatients with AN

RCT

Cognitive flexibility, central coherence performance

105

Herzog et al., 2022 [120]

Germany

247

 

Outpatient (adult, females)

To evaluate the long-term outcomes of a well described and fairly homogeneous sample of adult patients with anorexia nervosa and, to examine whether the treatment advantages found at the 1-year follow-up would persist more than 4 years later

Longitudinal

BMI, eating pathology, mental health outcomes

106

Hibbs et al., 2015 [121]

UK

 

13

Community (mixed cohort, both sexes)

To perform a meta-analysis of quantitative studies that have described the impact of interventions on caregivers

Meta-analysis

Level of carer distress and carer burden; expressed emotion

107

Hilbert et al., 2015 [122]

USA

205

 

Outpatient (adults, both sexes)

To analyse effects of rapid response across different treatments for BE disorder

RCT

Rates of remission from binge-eating, Global Eating Disorder Psychotherapy Pathology at posttreatment, 6, 12,18 and 24-month follow ups

108

Hilbert et al., 2019 [123]

Worldwide

7515

81

Community (adult, both sexes)

To provide a meta-analysis on the efficacy of psychological and medical treatments for BED

Meta-analysis

Binge-eating episodes and abstinence from binge eating plus secondary outcomes; ED psychopathology and body image, and general psychopathology

109

Hill, Craighead and Safer, 2011 [124]

USA

32

 

Outpatient (adult, females)

To investigate a modified version of DBT for BN, entitled appetite focused DBT

RCT

Rate of response to treatment and number of BN symptoms

110

Hodsoll et al., 2017 [125]

UK

149

 

Outpatients (adolescents, both sexes)

To examine the impact of Collaborative Care Skill Training Workshops on carers’ coping strategies etc., as well as unexplored dimension of accommodating and enabling of their loved one's ED behaviour

RCT

Level of Carer skills; accommodation and enabling behaviour; time spent care giving; body mass index; frequency of admissions

111

Högdahl, Birgagard and Bjorck, 2013 [126]

Sweden

79

 

Outpatient/inpatient (adults, both sexes)

To investigate the effects of a bibliotherapy-based CBT-based guided self-help with internet support in a clinical setting

Repeated measures (without follow up)

Pre and post treatment symptoms measured by the Eating Disorder Questionnaire (EDE-Q) and the Eating Disorder Inventory 2

112

Högdahl et al., 2023 [127]

Sweden

150

 

Outpatient (adults, both sexes)

To evaluate effects of two types of internet-based cognitive behavioural therapy and a structured day patient program, the latter being a standard treatment at an eating disorder clinic at the time for the study

RCT

ED pathology, self-image, clinical impairment

113

Hoyle et al., 2013 [128]

Australia

37

 

Community (Mixed Cohort, Both sexes)

To perform a meta-analysis of quantitative studies that have described the impact of interventions on caregivers

RCT

Carer distress, high-expressed emotion (EE), and care-giving burden associated with ED symptoms

114

Hughes et al., 2014

Australia

N/A

 

Outpatient (adolescents, both sexes)

To describe the change experienced within a multidisciplinary specialist ED service when a new model of care was implemented

Case study

Admission rate, re-admission rate, number of total bed days, completion of treatment, program success

115

Hughes et al., 2018 [129]

Australia

198

 

Outpatient (adolescents, both sexes)

To examine attendance patterns of families in FBT and the impact on outcome

Case series

Weight and ED symptoms at end of treatment

116

Hughes et al., 2017 [130]

Australia

42

 

Outpatient/inpatient (adolescents, both sexes)

To examine engagement in and outcomes of FBT for adolescents with atypical anorexia nervosa

Case series

Engagement in FBT (i.e., length and dose of treatment), reduction in ED symptoms as measured by the EDE, reduction in psychological symptoms (i.e., CDI, RSE, YBC-EDS, and CYBOCS), absence of binge eating and purging, return of menses and change in weight

117

Jansingh et al., 2020 [5]

N/A

 

3

Outpatient (mixed cohort, both sexes)

To overview the recent literature on psychological treatment for young adults/adults with AN and discuss the implications of the findings for clinical practice

Review (narrative)

Available treatment outcomes and their effectiveness

118

Jenkins et al., 2021 [131]

UK

180

 

Outpatient (adults, both sexes)

To investigate the effectiveness and cost-effectiveness of guided self-help via face-to-face meetings and a more scalable method, providing support via email

RCT

Overall severity of eating psychopathology and for cost-effectiveness, binge-free using symptom abstinence

119

Jenkins, Morgan and Houlihan, 2019 [132]

UK

63

 

Outpatient (adult, both sexes)

To investigate the effectiveness of CBT for EDs in a 'real-world' setting

Quasi-experimental (intervention)

Height and weight, and remission

120

Jewell et al., 2016 [133]

Worldwide

 

13

Outpatient (mixed cohort, both sexes)

To critically review the evidence for ED-focused family therapy using a modern paradigm

Review (critical)

Varied

121

Jones and Clausen, 2013 [134]

Denmark

205

 

Outpatient (mixed cohort, females)

To evaluate the efficacy of a brief group CBT program in treating a large cohort of patients diagnosed with BN

Repeated measures (without follow up)

Bulimia-related behavioural symptoms and bulimia-related distress using EDE

122

Jones et al., 2012 [135]

UK

48

 

Outpatient (adults, both sexes)

To investigate outcomes of a Guided Self-Help (GSH) programme for BE; and to compare profiles of treatment completers and non-completers; and to qualitatively explore reasons for non-completion

Case study

Gender, age, height and weight; Eating Disorder Examination (EDE), Eating Disorder Examination-Questionnaire (EDE-Q), Beck Depression Inventory-2 (BDI), Work and Social Adjustment Scale (WSAS)

123

Juarascio et al., 2013 [136]

USA

140

 

Inpatient (adult, females)

To examine the efficacy of an Acceptance and Commitment Therapy (ACT) based group treatment for ED's and to see if the addition of ACT residential groups to TAU would improve treatment outcomes

RCT

Disordered eating using the Eating Disorder Examination Questionnaire (EDE-Q)

124

Juarascio et al., 2022 [137]

USA

56

 

Community (adults, all sexes)

To assess the feasibility and acceptability of the CBT + system when used in conjunction with CBT, evaluate the ability of the Just-in-time, adaptive interventions (JITAIs) within the CBT + system to improve skill utilization, examine pre- to post-treatment changes in ED symptoms among individuals receiving JITAIs alongside CBT+, and provide a preliminary estimate of the independent efficacy of JITAIs within the CBT + system to inform design of a future fully powered randomized controlled trial

Quasi-experimental (intervention)

Eating pathology, participant skill use, app usage, acceptability

125

Juarascio et al., 2023 [138]

USA

59

  

To test a novel treatment approach for binge eating targeting reward imbalance, called Reward Re-Training (RRT), in comparison to a therapeutic attention control condition (supportive psychotherapy)

RCT

ED symptoms, depressive symptoms, alcohol and substance use, quality of life

126

Juarascio, Forman and Herbert, 2010 [139]

USA

55

 

Outpatient (adults, both sexes)

To examine several questions related to the treatment of eating pathology within the context of a larger RCT that compared standard CBT

RCT

The severity of depressive symptoms (BDI-II), anxiety (BAI), Eating Pathology (EPI), life satisfaction (QOLI), level of functioning (GAF, APA, 2000)

127

Kaidesoja, Cooper and Fordham, 2022 [140]

Worldwide

 

44

Mixed (adults, both sexes)

To map and examine the systematic review evidence base regarding the effects of cognitive-behavioural therapy (CBT) for eating disorders (EDs), especially against active interventions

Review (systematic)

ED behaviours and psychopathology

128

Kambanis and Thomas, 2023 [141]

Worldwide

 

N/A

Mixed (mixed cohorts, both sexes)

To review the literature pertaining to the assessment and treatment of avoidant/restrictive food intake disorder (ARFID) 10 years following its introduction to DSM-5

Review (narrative)

Psychological evaluation, medical evaluation, treatment, comorbidities, family-based approach, comorbidities, other treatment approaches

129

Karekla, Nikolaou and Merwin, 2022 [142]

USA

92

 

Community (young people, females)

To evaluate an innovative digital gamified Acceptance and Commitment early-intervention program (AcceptME) for young females showing signs and symptoms of an ED and at high risk for an ED

RCT

Weight Concern Scale, Eating Disorder Diagnostic Scale, EDE-Q, quality of life, body dissatisfaction and feelings of being fat, body-image related thoughts and feelings, Body Image Avoidance Questionnaire

130

Katterman et al., 2014 [143]

Worldwide

 

14

Outpatient (adults, both sexes)

To review 14 studies that investigated mindfulness meditation as the primary intervention and assessed binge eating, emotional eating, and/or weight change

Review (systematic)

Binge-eating, emotional-eating and/or weight change

131

Katzman et al., 2010 [144]

USA

225

 

Outpatient (adult, both sexes)

To conduct a RCT in the treatment of BN, comparing CBT versus motivational enhancement and followed by group versus individual CBT

RCT

Patient improvement

132

Keegan, Tchanturia and Wade, 2021 [145]

Worldwide

 

63

Mixed (adult, both sexes)

To compare previously documented inefficiencies in central coherence and set-shifting between people with non-underweight EDs and people with AN

Systematic review/meta-analysis (combined)

Central coherence, set-shifting

133

Kelly and Carter, 2015 [146]

Canada

41

 

Outpatient (adults, both sexes)

To compare a compassion-focused therapy-based self-help intervention for BED to a behaviourally based intervention

RCT

Body-Mass Index, EDE-Q, Binge Eating Frequency, Self-Compassion Scale

134

Klein, Skinner and Hawley, 2013 [147]

USA

N/A

 

Outpatient (adults, females)

To examine two condensed adaptations of dialectical behaviour therapy for BE

RCT

Core binge-eating symptoms and bulimic symptoms, interoceptive awareness

135

Knott et al., 2015 [148]

UK

272

 

Outpatient (adult, both sexes)

To evaluate treatment outcomes with CBT for adults with bulimia and to compare this with a previously published RCT

Case series

Measurement of ED psychotherapy using EDE-Q scores

136

Konig et al., 2018 [149]

Germany

147

 

Outpatient (mixed cohort, both sexes)

To determine the cost-effectiveness of individual face-to-face CBT compared to therapist guided Internet-based self-help in overweight or obese adults with BED

RCT

Long-term effectiveness (measured in Binge-free days) as well as the development of costs beyond the end of treatment, over a 22-month observation period

137

Kroger et al., 2010 [150]

Germany

24

 

Inpatient (adult, females)

To determine if adapted dialectical behaviour therapy for borderline personality disorder and EDs might improve disorder related complaints

Repeated measures (with follow up)

Remission rate, mean body weight

138

Lammers et al., 2022 [151]

Netherlands

175

 

Community (adults, both sexes)

To evaluate whether the results of a quasi-randomized study, comparing dialectical behavior therapy for binge-eating disorder (DBT-BED) and an intensive, outpatient cognitive behaviour therapy (CBT +) in individuals with BED, would be replicated in a nonrandomized study with patients who more closely resemble everyday clinical practice

Quasi-experimental (intervention)

ED pathology, emotion regulation, general psychopathology

139

Lampard, 2011 [152]

Australia

162

 

Outpatient (adult, females)

To compare and evaluate the original and the enhanced cognitive-behavioural models of BN using structural equation modelling

Cross-sectional

Variables outlined in the original CB-BN model, self-esteem, perfectionism, mood intolerance, interpersonal problem

140

Lane-Loney et al., 2022 [153]

USA

81

 

Inpatient (adolescents, both sexes)

To describe our protocol for treating ARFID at our PHP, to provide case studies exemplifying how our treatment protocol is modified for each unique ARFID presentation, and to explore the relative effectiveness of our treatment program for three different ARFID presentations

 

Anthropometrics, food acceptance/fear survey, anxiety symptoms, depressive symptoms,

141

Lavender et al., 2012 [154]

UK

74

 

Outpatient (adults, both sexes)

To test a novel treatment based on a hypothesis that a focus on broader emotional and social/interpersonal issues underlying ED's would increase treatment efficacy, on an Emotional and Social Mind Training Group, against a CBT Group treatment

RCT

EDE global score

142

Lazaro et al., 2011 [155]

Spain

160

 

Outpatients (adolescents, both sexes)

To evaluate self-esteem and social skills in adolescent ED patients before/after specific group therapy in a Day Hospital Programme

Case study

The Piers–Harris Children’s Self-Concept Scale (PHC-SCS), the Self-Esteem in Eating Disorders Questionnaire (SEED) and the Socialization Battery (BAS-3), at the beginning of group therapy, and after the completion of 8-sessions

143

Le et al., 2017 [156]

Australia

N/A

 

Community (adult, both sexes)

To model the cost-effectiveness of specialist-delivered CBT for BN compared to no intervention

Modelling (statistical)

Cost of treatment and services, remission rate, health outcome

144

Le et al., 2017 [157]

Australia

N/A

 

Outpatient (adolescents, both sexes)

To evaluate the cost-effectiveness of FBT compared to adolescent-focused individual therapy or no intervention

Modelling (statistical)

Incremental cost effectiveness

145

Le Grange et al., 2012 [158]

USA

121

 

Outpatient (adolescents, both sexes)

To identify treatment moderators and mediators of remission for adolescents with AN via FBT and individual adolescent focused therapy

RCT

Severity of ED pathology using the EDE V12.0; depressive symptoms using the BECK Depression Inventory (BDI) and body weight

146

Le Grange et al., 2015 [159]

USA

130

 

Outpatient (adolescents, both sexes)

To compare the relative efficacy of therapies of FBT for adolescent bulimia nervosa and CBT adapted for adolescents

RCT

Abstinence of Binge-eating rates and purging for 4 weeks before assessment using the EDE

147

Le Grange et al., 2016 [160]

Australia

107

 

Outpatient (adolescents, both sexes)

To compare the relative efficacy of FBT and parent-focused treatment

RCT

Remission defined as ≥ 95% of median body mass index and Eating Disorder Examination Global Score within 1SD of community norms

148

Levinson et al., 2015 [161]

USA

36

 

Outpatient/inpatient (mixed cohort, both sexes)

To examine D-cycloserine-facilitation of exposure therapy would increase body mass index in patients with AN

RCT

Body Mass Index (BMI), anxiety using the Subjective Units of Distress Scale (SUDS)

149

Linardon et al., 2017 [162]

Worldwide

 

27

Outpatient (adult, both sexes)

To examine the empirical status of third-wave behaviour therapies

Systematic review/meta-analysis (combined)

ED Psychopathology, EDE global score, remission/recovery, binge eating, shape concern, depression, self-esteem

150

Linardon et al., 2017 [163]

Worldwide

 

79

Community (mixed cohort, both sexes)

To examine the efficacy of CBT on eating disorders

Systematic review/meta-analysis (combined)

The efficacy of CBT for ED

151

Linardon et al., 2017 [164]

Worldwide

 

26

Mixed (mixed cohort, both sexes)

To examine the efficacy of psychotherapy for BN on depressive symptoms in the short- and long-term

Systematic review/meta-analysis (combined)

Efficacy of psychotherapy on symptoms of depression

152

Linardon et al., 2020 [165]

Australia

 

36

Inpatient and outpatient (mixed cohort, both sexes)

To conduct an updated meta-analysis on the efficacy of e-mental health interventions for treating and preventing eating disorders

Systematic review/meta-analysis (combined)

Efficacy of e-mental health interventions paying attention to trial quality and outcomes

153

Linardon et al., 2022 [166]

Australia

332

 

Outpatient (adults, both sexes)

To develop and evaluate a smartphone app based on the principles and techniques of transdiagnostic CBT for eating disorders

RCT

Global levels of ED psychopathology; other ED symptoms, impairment and distress

154

Linardon, 2018 [167]

Australia

 

29

Community (adult, both sexes)

To examine whether CBT can modify dietary restraint and attitudes towards shape and weight

Meta-analysis

Dietary restraint and dysfunctional attitudes towards shape and weight

155

Linardon, Kothe and Fuller-Tyszkiewicz, 2019 [168]

Worldwide

 

34

Outpatient (adult, both sexes)

To examine the effects of psychotherapy for bulimia nervosa and binge-eating disorder on self-esteem

Meta-analysis

The effects of psychotherapy for BN and BED on self‐esteem improvement

156

Linardon, Messer and Fuller-Tyszkiewicz, 2018 [167]

Australia

 

27

Outpatient (adult, both sexes)

To conduct a meta-analysis of nonrandomized studies of cognitive behaviour therapy (CBT) for EDs

Meta-analysis

Abstinence rates of binge-eating

157

Linnet et al., 2022 [169]

Denmark

143

 

Community (adults, both sexes)

To investigate the association between the number of words per message and adherence in a text based iCBT program for BED

Quasi-experimental (intervention)

BED symptoms, depressive symptoms

158

Lock et al., 2010 [170]

USA

121

 

Outpatient (adolescents, both sexes)

To evaluate the relative efficacy of FBT and adolescent-focused individual therapy for adolescents with AN

RCT

Full remission or partial remission rates; mean global Eating Disorder Examination Score within one SD of published means

159

Lock et al., 2015 [171]

USA

45

 

Outpatient (adolescents, both sexes)

To examine the feasibility and effects of treatment aimed at enhancing parental self-efficacy related to re-feeding skills in poor early responders to FBT

RCT

Recruitment and attrition rates, percentile body weight, Therapy Suitability and Patient Expectancy (TSPE) Scale, Psychopathology (EDE)

160

Loeb et al., 2012 [172]

N/A

 

N/A

Outpatient (adolescents, both sexes)

To describe the transdiagnostic theory and application of FBT for children and adolescents with EDs

Review (narrative)

Not defined

161

Low et al., 2021 [173]

Worldwide

 

6

Inpatient and outpatient (mixed cohort, both sexes)

To examine the efficacy of virtual reality-enhanced CBT in the treatment of binge-purging type EDs compared to CBT

Meta-analysis

BMI and frequency of binges and/or purges; body satisfaction; situation induced body dissatisfaction

162

Lydecker and Grilo, 2016 [174]

USA

344

 

Outpatient (mixed cohort, both sexes)

To examine differences in child ED behaviours and parental feeding practices between parents exhibiting AN, BN, binge-eating/purging disorder with parents reporting no ED characteristics

Cross-sectional

BMI, Eating Disorder Examination (EDE), Child Feeding Questionnaire (CFQ)

163

Lynch et al., 2010 [175]

USA

123

 

Outpatient (mixed cohort, both sexes)

To conduct an incremental cost-effectiveness analysis of a CBT guided self-help intervention to treat recurrent BE compared to TAU

RCT

Binge-free days and quality-adjusted life years (QALYs); cost to patients and the health plan

164

Macdonald et al., 2012 [176]

Worldwide

 

13

Outpatient (adults, both sexes)

To examine the context and effectiveness of motivational interviewing and Motivational Enhancement Therapy in patients or carers of people with ED's to identify limitations, difficulties and research needs

Review (systematic)

Varied

165

MacDonald, Trottier and Olmsted, 2017 [177]

Canada

104

 

Outpatient (adults, both sexes)

To examine whether rapid change in emotion regulation predicted treatment outcomes, beyond the effects of RSBC

Repeated measure (without follow-up)

Eating Disorder Examination Questionnaire (EDE-Q), Self-monitored ED behaviours, Difficulties in Emotion Regulation Scale (DERS), Beck Depression Inventory (BDI)

166

Madden et al., 2015 [178]

Australia

69

 

Outpatient (adolescents, both sexes)

To Identify whether early weight gain in family-based treatment (FBT) predicted greater weight and remission at end of FBT and 12-month follow-up

RCT

Weight gain

167

Magson, Handford and Norberg, 2021 [179]

Worldwide

 

20

Outpatient (mixed cohort, both sexes)

To determine the need for higher quality research that utilizes larger samples/uniform outcome measures that are more strongly grounded in theory

Review (systematic)

Changes in eating behaviours, cue reactivity and/or CS-US expectancies from pre- to post-treatment

168

Mallorqui-Bague et al., 2018 [180]

Spain

507

 

Outpatient (adult, females)

To explore Emotion Regulation difficulties and to assess pre-treatment and post-treatment changes among ED types

Longitudinal (< 5 years)

Pre-treatment and post-treatment changes among ED types

169

Månsson, Parling and Swenne, 2016 [181]

Sweden

47

 

Outpatient (adolescents, both sexes)

To study the effect of defined parental interventions on restrictive EDs in adolescents

Repeated measures (without follow up)

Weight change and Eating Disorder Examination Questionnaire at 1 week, 1 month, 3 months; EDE-Q score at start of treatment and at 3 months

170

Marco, Perpina and Botella, 2013 [182]

Spain

34

 

Outpatient (mixed cohort, females)

To compare CBT for EDs with/without a component for body image treatment using Virtual Reality techniques

RCT

Body-image; Body Attitude Test (BAT), Body Image Automatic Thoughts Questionnaire (BIATQ), Body Areas Satisfaction Scale (BASS), Situational Inventory of Body-Image Dysphoria (SIBID), The Bulimic Investigatory Test, Edinburgh (BITE), The Eating Attitudes Test (EAT)

171

Marcos and Cantero, 2009 [183]

Spain

98

 

Outpatient (mixed cohort, females)

To assess social support dimensions in patients with ED, looking at diagnosis, socio-demographic and clinical characteristics, and self-concept

Cross-sectional

Social support assessment

172

Masheb, Grilo and Rolls, 2011 [184]

USA

50

 

Outpatient (adult, both sexes)

To examine a dietary approach for producing weight loss in obese patients with BED who also received CBT

RCT

Percentage of participants achieving at least a 5% weight loss using BMI; Binge-remission, energy density, psychopathology using EDE

173

Mason et al., 2017 [185]

USA

171

 

Community and outpatient (adult, both sexes)

To examine baseline and longitudinal associations between eating-related and psychosocial variables and dimensions of weight QOL

RCT

Body mass index (BMI), ED psychopathology, and psychosocial factors

174

Matthews et al., 2018 [186]

USA

51

 

Community (mixed cohort, both sexes)

To examine the relation between caregiver illness perceptions about AN, symptom severity indicators, and caregiver burden in a sample of medically hospitalized youth with AN

Cross-sectional

Brief Illness Perceptions Questionnaire (Brief IPQ), Eating Disorder Symptom Impact Scale (EDSIS), Eating Disorder Examination-Questionnaire (EDE-Q), Children's Depression Inventory-2 Short Form (CDI-2-S), Multidimensional Anxiety Scale for Children-Second Edition (MASC-2)

175

McClay et al., 2016 [187]

UK

253

 

Mixed (mixed cohort, both sexes)

To investigate attitudes towards online self-help for ED's and the support required

Cross-sectional

Attitudes towards on-line self-help

176

McIntosh et al., 2011 [188]

New Zealand

135

 

Outpatient (adult, females)

To identify any evidence of a conditioned inoculation from exposure treatment compared with relaxation training in long-term abstinence from binge eating

RCT

Long-term abstinence rates and frequency of purging from binge-eating over 5 years

177

McIntosh et al., 2016 [189]

New Zealand

112

 

Outpatient (adult, females)

To compare CBT with CBT; schema therapy, and appetite-focused CBT

RCT

Frequency of binge-eating; some behavioural and psychological aspects

178

Mercado et al., 2021 [190]

UK

 

12

Mixed (adult, both sexes)

To examine randomised controlled trials (RCTs) comparing the efficacy of MBIs with control groups primarily encouraging either dietary or exercise-based behavioural change in individuals with overweight/obesity and/or binge eating disorder (BED)

Systematic review/meta-analysis (combined)

Changes in body mass (BMI or weight), mindfulness scores, BED symptoms

179

Moberg et al., 2021 [191]

Norway

 

62

Mixed (adults, both sexes)

To shed light on how these two specific and conceptually different treatment approaches work for patient samples with varying presentations of EDs in both RCTs and observational studies

Review (meta-analysis)

ED psychopathology, ED remission

180

Moghmi, Davis and Rotondi, 2021 [192]

Worldwide

 

3

Community (adults, both sexes)

To determine the effectiveness of eHealth treatments in adults diagnosed with full or subthreshold BED

Systematic review/meta-analysis (combined)

Objective binge episodes, BMI, EDE-Q, shape concern, weight concern

181

Monteleone et al., 2022 [193]

Worldwide

 

59

Mixed (mixed cohorts, both sexes)

To conduct a review accounting for effect modifiers and confounding factors, and conducting analyses by age group, type of intervention, setting, control condition, ED diagnosis (i.e. AN, BN, BED, EDNOS), and mode of treatment delivery

Meta-analysis

ED-specific behaviours, neuropsychological functioning, eating disorder-specific psychopathology, functioning and quality of life, general psychiatric symptoms, global course of the disease, weight or BMI

182

Munsch, Meyer and Biedert, 2012 [194]

Switzerland

48

 

Community (adult, both sexes)

To assess the long-term efficacy of Cognitive-Behavioural Treatment (CBT) and Behavioural Weight-Loss-Treatment (BWLT) in patients with BED and to identify potential predictors of long-term treatment success

RCT

ED psychopathology, BMI, negative affect, therapeutic process variables and contentment with therapy

183

Murphy et al., 2012 [195]

N/A

 

N/A

Outpatient (mixed cohort, both sexes)

To consider, review and discuss the rationale for using Interpersonal psychotherapy to treat patients with EDs

Review (narrative)

Evidence supporting the use of IPT

184

Murray et al., 2015 [196]

USA

35

 

Outpatient/inpatient (adolescents, both sexes)

To investigate the efficacy of integrating FBT and dialectical behaviour therapy in treating adolescent bulimia nervosa

Repeated measures (no follow up)

Core bulimia nervosa pathology; emotional regulation difficulties; parental measures of self-efficacy

185

Onnink et al., 2022 [197]

USA

22

674

Mixed (mixed cohorts, both sexes)

To review the evidence of Acceptance and Commitment Therapy (ACT) for EDs through January of 2022

Review (systematic)

ED behaviour, body image, weight

186

O’Reilly et al., 2014 [198]

Worldwide

 

21

Outpatient (adults, both sexes)

To conduct a literature review to determine the effectiveness of mindfulness-based interventions for treating binge eating, emotional eating and external eating

Review (systematic)

Changing obesity-related eating behaviours, specifically binge eating, emotional eating and external eating

187

Pacanowski et al., 2018 [199]

USA

189

 

Outpatient (adult, both sexes)

To characterise factors that promote or inhibit weight loss in individuals with BED and obesity

RCT

BMI, Eating Disorder Examination (EDE), Three Factor Eating Questionnaires (TFEQ)

188

Palavras et al., 2017 [200]

Worldwide

 

19

Outpatient (adult, both sexes)

To review efficacy of psychological therapies for BN and BED in reducing binge frequency and weight

Meta-analysis

Binge-eating frequency or binge remissions; weight or BMI at end of treatment and at 1 year follow up; treatment completion rates

189

Palavras et al., 2021 [201]

Brazil

98

 

Outpatient (adults, both sexes)

To investigate the efficacy and safety of introducing a weight loss intervention to the treatment of people with disorders of recurrent binge eating and a high BMI

RCT

Sustained weight loss at 12 months, ED psychopathology

190

Parling et al., 2016 [202]

USA

43

 

Outpatient (adult, both sexes)

To compare 19 sessions of ACT with TAU, after 9 to 12 weeks of day care, regarding recovery and risk of relapse up to 5 years

RCT

Body Mass Index (BMI) and specific eating psychopathology

191

Paslakis et al., 2017 [203]

Germany

30

 

Outpatient (females)

To determine if the novel virtual reality paradigm may serve as a therapeutic tool for exposure and habituation of the urge of acutely engaging in physical activity in patients with EDs

Cross-sectional

Cognitive, emotional, and behavioural aspects of the acute urge to move, leptin levels

192

Peat et al., 2017 [204]

Worldwide

 

30

Community (adult, both sexes)

To expand the literature for BED studies to include a review of comparative effectiveness

Review (systematic)

Abstinence, frequency, weight

193

Pennesi and Wade, 2016 [3]

Worldwide

 

54

Community (adult, females)

To identify existing models for disordered eating and to identify those models which have helped inform the development of interventions for disordered eating

Review (systematic)

Disordered eating models (existing and those that informed the development of interventions for disordered eating)

194

Pepin and King, 2016 [205]

Australia

77

 

Community (mixed cohort, both sexes)

To examine if Collaborative Care Skills Training workshops by facilitators trained in its delivery could lead to improve the well-being, coping strategies and problem-solving skills of carers of someone with an ED

Repeated measures (with follow up)

Coping strategies, expressed emotion (EE), burden, distress, confidence in capacity to change, accommodating and enabling of ED behaviour

195

Pepin and King, 2013 [206]

Australia

15

 

Community (mixed cohort, both sexes)

To present the results of a RCT measuring the efficacy of a video-based skills training to decrease burden and psychological distress in caregivers of inpatients treated for an ED in specialized hospital units

Repeated measures (with follow up)

General psychological health (psychological distress), adaptive and maladaptive coping, expressed emotion (critical comments and emotional over involvement), burden experienced by carers and perceptions of impact of caring for someone with an ED (nutritional difficulties, guilt, manifestation of dysregulated behaviour, social isolation)

196

Perpina et al., 2013 [207]

Spain

59

 

Outpatient (adult, females)

To examine the clinical validation of a Virtual Reality Environment designed to normalize eating patterns in EDs

Control trial

The Reality Judgment and Presence Questionnaire (RJPQ); The revised version of the ITC-Sense of Presence Inventory (ITC-SOPI); Beck Depression Inventory (BDI-II); Beck Anxiety Inventory (BAI); The Restraint Scale (RS)

197

Peterson et al., 2017 [208]

USA

80

 

Outpatient (adult, both sexes)

To examine the indirect effects of Integrative Cognitive-Affective Therapy and CBT-E on BN treatment outcome through the variables of emotion regulation, self-directed behaviour, and self-discrepancy

RCT

EDE Binge-eating and Purging frequency as well as global score at end of treatment and 4-month follow up

198

Peterson et al., 2020 [209]

USA

112

 

Outpatient (adult, both sexes)

To compare Integrative Cognitive-Affective Therapy with an established cognitive-behavioural guided self-help treatment using standard and ecological momentary assessment outcome measures

RCT

Frequency of binge eating as measure by the EDE and EMA (hypothesised maintenance mechanisms also assessed)

199

Philipp et al., 2021 [210]

Austria

98

 

Outpatient (adolescent, both sexes)

To evaluate the effectiveness of a caregivers’ skills training program on adolescents with AN delivered as workshops or online

Repeated measures (without follow up)

BMI, eating psychopathology, motivation to change, emotional and behavioural problems and quality of life

200

Pinto-Gouveia et al., 2017 [211]

Portugal

59

 

Outpatient (adult, females)

To test the acceptability and efficacy of a psychological program based on psychoeducation, mindfulness, and self-compassion for obese or overweight women with BED

Longitudinal (< 5 years)

EDE 16.0, Binge Eating Scale, Beck Depression Inventory, Shamer Scale, Obesity-Related Well-Being Questionnaire, Body Image-Acceptance and Action Questionnaire

201

Pisetsky et al., 2015 [212]

USA

190

 

N/A

To examine whether perceptions of group dynamics early in treatment predicted ED outcomes in adults with BED in 15 CBT group sessions with differing levels of therapist involvement (led, assisted, and self-help)

RCT

EDE Global Score, Number of OBE in past 21 days

202

Pittock, Hodges and Lawrie, 2018

Worldwide

 

5

Outpatient (adult, females)

To review if internet-delivered CBT as a possible treatment for patients with bulimic symptoms

Review (systematic)

Binge-eating and purging

203

Polnay et al., 2014 [213]

Worldwide

 

10

Mixed (mixed cohort, both sexes)

To evaluate how group therapy for BN compares with individual therapy, no treatment, or other therapies, in terms of remission from binges and binge frequency

Systematic review/meta-analysis (combined)

Remission from binges and binge-frequency

204

Poulsen et al., 2014 [214]

Denmark

70

 

Outpatient (adult, both sexes)

To compare psychoanalytic psychotherapy and CBT in the treatment of BN

RCT

Eating disorder examination interview at baseline, after 5 months and after 2 years

205

Puls, Schmidt and Hilbert, 2019 [215]

Germany

64

 

Outpatient (young people, both sexes)

To examine therapist adherence and therapeutic alliance and their associations in CBT for adolescents with BED

RCT

Variability of adherence and alliance) explained by treatment module, patient, and therapist)

206

Quadflieg et al., 2017 [216]

Germany

285

 

Community (mixed cohort, both sexes)

To investigate the feasibility and usefulness of an online information and skills development intervention for carers of individuals with AN and individuals with AN

RCT

Eating Disorder Symptom Impact Scale, Accommodation and Enabling Scale and General Health Questionnaire-12 at baseline and 3-month follow up

207

Rahmani et al., 2018 [217]

Iran

60

 

Outpatient (adult, females)

To determine the effect of dialectical behaviour therapy on BED, difficulties in emotion regulation, and BMI of patients suffering from BED and overweight

RCT

BMI, binge eating and emotion regulation ability

208

Ramklint et al., 2012 [218]

Sweden

89

 

Mixed (mixed cohort, both sexes)

To describe the implementation and effectiveness of the first step, guided self-help of a stepped-care model of CBT for patients with bulimic symptoms

Case series

Decrease in bulimic symptoms

209

Raykos et al., 2014 [219]

Australia

112

 

Outpatient (adult, both sexes)

To assess therapeutic alliance over the course of CBT-E for patients with a diagnosis of BN or atypical BN

Cross-sectional

Alliance, treatment retention and outcome

210

Raykos et al., 2014 [220]

Australia

406

 

Mixed (mixed cohort, both sexes)

To examine whether baseline interpersonal problems differed across ED diagnoses and subtypes

Cross-sectional

Eating-disorder psychopathology and socialising ability

211

Ricca et al., 2010 [221]

Italy

144

 

Outpatient (adult, both sexes)

To compare individual and group CBT for BED

RCT

Recovery at 3-year follow-up, weight-loss, treatment resistance, relapse, and diagnostic change

212

Richards et al., 2018 [222]

Worldwide

 

30

Outpatient (adolescents, both sexes)

To review the literature reporting outcomes of augmentative FBT interventions for adolescents with restrictive EDs

Review (systematic)

Body weight and/or ED symptoms at end of treatment

213

Rieger et al., 2010 [223]

N/A

 

N/A

N/A

To develop a theoretical model of interpersonal psychotherapy in the context of EDs

Review (narrative)

Social Evaluation

214

Riesco et al., 2018 [224]

Spain

176

 

Outpatient (adult, both sexes)

To examine features of Other Specified Feeding or EDs subtypes, CBT responses and clinical predictors of therapy outcome

Case series

Eating related psychopathological and personality measures

215

Robinson et al., 2013 [225]

Canada

49

 

Outpatient (adolescents, both sexes)

To examine parent and adolescent outcomes of FBT and the role of parental self-efficacy in adolescent ED, depressed mood and anxiety symptoms

Repeated measures (with follow up)

Changes in ED symptomatology, as well as in ratings of depressed mood and anxiety symptoms

216

Romero-Martinez, Ruiz-Robledillo and Moya-Albiol, 2016 [226]

Spain

54

 

Community (adult, both sexes)

To characterize whether caregivers of individuals with EDs show declarative memory impairments compared to non-caregiver’s caregivers

Cross-sectional

Memory impairment Rey Auditory Verbal Learning Test (RAVLT), General Health Questionnaire (GHQ-28), Level of testosterone (T)

217

Rossi et al., 2021 [227]

Italy

141

 

Outpatient (adult, females)

To evaluate the role of its variation as a possible mediator of the efficacy of enhanced CBT on classic ED symptomatology, including body uneasiness

Longitudinal (< 5 years)

BMI and psychometric scales (EDE-Q6, BUT-A, IDEA, SCL 90-R, GSI)

218

Rozakou-Soumalia, Dȃrvariu and Sjögren, 2021 [228]

Denmark

 

11

Mixed (adult, both sexes)

To study the effect of DBT in ED and specifically the effect of DBT on ER in comparison to a control group and to investigate the effect on general psychopathology and Body Mass Index (BMI)

Systematic review/meta-analysis (combined)

Emotion regulation, ED psychopathology, BMI

219

Sanchez-Ortiz et al., 2011 [229]

UK

76

 

Outpatient (adult, females)

To evaluate if Internet-based CBT may be able to bridge the gap of female students who do not access effective treatment

RCT

ED outcomes were assessed with the ED examination (EDE); depression, anxiety and quality of life

220

Scanferla et al., 2022 [230]

France

169

 

Outpatient (adult, both sexes)

To test this novel intervention assuming it would be an innovative “first fast” step into care, facilitating access and commitment in specialised treatment of users with newly diagnosed eating disorders

Quasi-experimental (intervention)

ED psychopathology, subjective satisfaction

221

Schag et al., 2019 [231]

Germany

80

 

Mixed (mixed cohort, both sexes)

To compare the results of a cognitive behavioural group intervention focusing on impulsive eating with a randomised control group

RCT

Binge-eating episodes; eating pathology, depression, general impulsivity and body-mass-index (BMI)

222

Schlegl et al., 2015 [232]

Worldwide

 

45

Outpatient (mixed cohort, both sexes)

To evaluate the potential of technology-based interventions in EDs (AN and BN) for prevention and treatment, and also for carers of ED patients

Review (systematic)

Varied

223

Schlup, Meyer and Munsch, 2010 [233]

Switzerland

76

 

Outpatient (adult, females)

To compare treatment outcomes of short-term and long-term CBT for BED in a non-randomized comparison and to identify moderators of treatment outcome

Repeated measures (with follow up)

Remissions from binge-eating based on EDE, number of OBEs (EDE), associated disorder psychopathology (4EDE sub scales) and BMI

224

Schwarte et al., 2017 [234]

Germany

296

 

Community (Mixed cohort, both sexes)

To assess the levels of expressed emotions and depressive symptoms found in caregivers of patients with AN

Longitudinal (< 5 years)

Levels of Expressed Emotions (EE) and Depressive Symptoms (DS)

225

Shimshoni et al., 2020 [235]

USA

14

 

Community (adult, both sexes)

To assess the feasibility, acceptability, treatment-satisfaction, and preliminary efficacy of Supportive Parenting for Anxious Childhood Emotions adapted for avoidant/restrictive food intake disorder

Repeated measure (without follow-up)

The feasibility, acceptability, treatment-satisfaction, and preliminary efficacy of Supportive Parenting for Anxious Childhood Emotions

226

Slade et al., 2018 [236]

Worldwide

 

21

Community (adult, both sexes)

To compare the effectiveness of pharmacological, psychological and a combination of treatments to identify the most effective for BN

Meta-analysis

Full remission at end of treatment

227

Sodersten et al., 2017 [237]

Worldwide

 

N/A

Mixed (adult, both sexes)

To examine the science and evidence supporting CBT for the treatment of BN and other EDs

Review (narrative)

Remission rate, relapse rate

228

Solmi et al., 2021 [238]

Worldwide

 

16

Outpatient (adult, both sexes)

To compare stand-alone psychological interventions for adult outpatients with AN with a specific focus on BMI, ED symptoms, and all-cause dropout rate

Systematic review/meta-analysis (combined)

BMI, Frequency of Eating Disorder Symptoms, Clinical symptoms and all-cause drop-out rate

229

Spielmans et al., 2013 [239]

Worldwide

 

53

Community (adult, both sexes)

To conduct meta-analysis comparing psychological treatments for BN and BED and the role of moderating variables

Meta-analysis

Therapist allegiance, supervision, pretraining, homework

230

Steele, Bergin and Wade, 2011 [240]

Australia

87

 

Mixed (mixed cohort, both sexes)

To examine predictors of guided self-help treatment outcome in BN

RCT

Stress, Eating Disorder-Related Automatic Thoughts, Frequency of Binge episodes

231

Stefanini et al., 2019 [241]

Italy

97

 

Community (adult, both sexes)

To study the factors affecting caregivers living with someone with an ED

Cross-sectional

The accommodation and enabling scale for eating disorders (AESED), The family questionnaire (FQ), The depression, anxiety and stress scale (DASS-21)

232

Stefini et al., 2017 [242]

Germany

81

 

Outpatient (adolescent, females)

To compare CBT and psychodynamic therapy for the treatment of BN in female adolescents

RCT

Rate of remission defined as a lack of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis at the end of therapy

233

Stein et al., 2013 [243]

USA

69

 

Outpatient (adult, females)

To determine if findings of a randomized trial of an identity intervention programme designed to build new positive self-schemas that are separate from other conceptions of the self in memory as the means to promote improved health in women diagnosed with EDs are reported

RCT

ED symptoms at 1-month, 6-months, 12-months post intervention

234

Steinberg et al., 2023 [244]

USA

210

 

Community (young people, both sexes)

To describe our FBT + treatment approach, highlight preliminary clinical outcomes, and discuss implications for the future of eating disorder treatment

Cross-sectional

Weight, ED symptoms, depression and anxiety symptoms, caregiver burden and self-efficacy, treatment acceptability and satisfaction

235

Steinglass et al., 2011 [245]

USA

 

N/A

Outpatient (mixed cohort, both sexes)

To review data on anxiety in AN, the relationship between anxiety disorders and AN, and the use of Exposure and Response Prevention in treatment

Review

Varied

236

Steinglass et al., 2014 [246]

USA

32

 

Inpatient (adult, both sexes)

To evaluate AN Exposure and Response Prevention (AN-EXRP) as an adjunctive strategy to improve eating behaviour during weight restoration

RCT

Average test meal caloric intake

237

Stice et al., 2019 [247]

USA

84

 

Outpatient (adult, females)

To evaluate a dissonance-based group ED treatment

RCT

ED diagnosis; ED symptom change; level of dissonance about affirming the thin-ideal

238

Stile-Shields et al., 2013 [248]

USA

64

 

Outpatient (adult, females)

To investigate the strength and role of therapeutic alliance by comparing CBT and Specialist Supportive Clinical Management for the treatment of AN

RCT

Perception of the quality of the therapeutic relationship, eating disorder (ED) symptomatology, and depressive symptomatology

239

Stiles-Shields et al., 2012 [249]

N/A

 

N/A

Outpatient (adolescent, both sexes)

To provide a critical literature overview focusing on FBT especially adolescents

Review (other)

Not defined

240

Strandskov et al., 2017 [250]

Sweden

92

 

Community (adult, both sexes)

To investigate the outcome of tailored and ACT-influenced, Internet CBT treatment for ED psychopathology, and the relation between knowledge acquisition and outcome

RCT

Eating disorder symptoms and body shape dissatisfaction

241

Striegel-Moore et al., 2010 [251]

USA

123

 

Outpatient (mixed cohort, both sexes)

To evaluate whether a manual-based guided self-help form of CBT, in 8 sessions over a 12-week period, is more effective than TAU

RCT

Patient Health Questionnaire eating disorder module (PHQ-ED); Eating Disorder Examination (EDE); Structured Clinical Interview for DSM-IV; Beck Depression Inventory

242

Swenne, Parling and Ros, 2017 [252]

Sweden

201

 

Outpatient/inpatient (adolescent, both sexes)

To investigate the 1-year outcome of a family-based intervention programme with defined and decisive interventions at the start of treatment

Repeated measures (with follow up)

BMI and psychometric measures (EDE-Q)

243

Tatham, 2011 [253]

N/A

 

N/A

Outpatient (adult, both sexes)

To consider theoretical and empirical findings in terms of the clinical applicability of imagery-based techniques and their ability to enhance CBT

Review (narrative)

Varied

244

Tecuta and Tomba, 2018 [254]

Italy

60

 

Outpatient (adult, females)

To investigate subjective incompetence and its association with psychological distress and well-being

Repeated measure (without follow-up)

Subjective incompetence

245

ter Huurne et al., 2015 [255]

Netherlands

214

 

Community (adult, females)

To evaluate the effects of a Web-based CBT using intensive asynchronous therapeutic to improve ED psychopathology, reduce body dissatisfaction and related health problems among ED patients

RCT

ED psychopathology; body dissatisfaction; physical health, mental health, self-esteem, quality of life, social functioning

246

ter Huurne et al., 2021 [256]

Netherlands

212

 

Community (adult, females)

To report on a 1-year follow-up study into a web-based CBT for female patients with ED

RCT with 1-year follow-up

ED psychopathology, body dissatisfaction, BMI, physical health, mental health, self-esteem, quality of life, social functioning

247

Thomas et al., 2017 [257]

N/A

 

N/A

Outpatient/inpatient (mixed cohort, both sexes)

To summarise what is known about avoidant/restrictive food intake disorder and to introduce a three-dimensional model

Review (other)

Not defined

248

Thomas et al., 2021 [258]

USA

17

 

Outpatient (adolescent, both sexes)

To evaluate feasibility, acceptability, and proof-of-concept for CBT for avoidant/restrictive food intake disorder in children and adolescents

Repeated measures (without follow-up)

Feasibility, acceptability, and proof-of-concept for CBT

249

Thomas, Wons and Eddy, 2018 [259]

N/A

 

N/A

Outpatient/inpatient (mixed cohort, both sexes)

To review the literature on avoidant/restrictive food intake disorder treatment and highlight a novel cognitive-behavioural approach

Review (other)

Not defined

250

Thompson-Breener, Boisseau and Satir, 2010 [260]

USA

120

 

Outpatient (adolescent, both sexes)

To undertake a naturalistic study of the treatment and outcome of adolescents with EDs in the community

Case series

Observation

251

Thompson-Brenner et al., 2015 [261]

USA

43

 

Community (adult, females)

To compare changes in purging, depression, and cognitive ED symptoms for associations with BN remission

Quasi-experimental (intervention)

Percentage change in purging frequency and percentage change in BDI score and Rate of Remission

252

Thompson-Brenner et al., 2016 [262]

USA

50

 

Outpatient (adult, both sexes)

To investigate the relative effects, predictors, and moderators of CBT for BN with personality and mood/anxiety disorders

RCT

Frequency of remission from binge-eating and purging at termination; severity of affective/interpersonal problems using EDE scores

253

Thompson-Brenner et al., 2021 [263]

USA

3108

 

Community (mixed cohorts, both sexes)

To examine the effect of the Renfrew Unified Treatment for Eating Disorders and Comorbidity (UT) implementation across 5 years of treatment delivery

Longitudinal (5-years)

ED symptom severity, depressive symptoms, experiential avoidance, anxiety sensitivity, mindfulness

254

Traviss, Heywood-Everett and Hill, 2011 [264]

UK

81

 

Outpatient (mixed cohort, both sexes)

To evaluate a CBT-based pack delivered by trained mental health professionals in 6 sessions over 3 months

RCT

Eating disorder psychopathology (EDE-Q), key behavioural features and global distress (CORE)

255

Traviss-Turner, West and Hill, 2017 [265]

Worldwide

 

30

Outpatient (mixed cohort, both sexes)

To establish the effectiveness of guided self-help for reducing global ED psychopathology and abstinence from BE, compared with controls

Systematic review/meta-analysis (combined)

Level of psychopathology and abstinence from binge eating

256

Treasure et al., 2015 [8]

Worldwide

 

N/A

N/A

To map the possibility of new treatment approaches for EDs

Review (narrative)

Primary and secondary symptoms seen in the enduring stage of ED

257

Turner, Bryant-Waught and Marshall, 2015 [266]

UK

94

 

Outpatient (adult, both sexes)

To explore the impact of early symptom change and the early therapeutic alliance on treatment outcome in CBT for EDs

Longitudinal (< 5 years)

Early symptom change (cognitive and behavioural) and the early therapeutic alliance on treatment outcome

258

Valenzuela et al., 2018 [267]

USA

110

 

Outpatient (adolescent, both sexes)

To examine the effect of FBT for BN and CBT on depressive symptoms and self-esteem in adolescents with BN

RCT

Depressive symptoms and self-asteem; Beck Depressive Inventory (BDI; Panel A) and Rosenberg Self‐Esteem Scale (RSES; Panel B)

259

Vancampfort et al., 2014 [268]

Belgium

34

 

Outpatient (adult, both sexes)

To explore the associations between changes in number of binges, physical activity, physical fitness, physical self-perception and QOL after 6-month physical activity counselling and CBT program in patients with BED

Repeated measures (without follow up)

Frequency of binges was assessed using the Eating Disorder Examination (EDE); Physical fitness: the 6-min walk test (6MWT); Health related quality of life: the MOS 36-item Short Form Health Survey (SF-36); Physical activity: Baecke Physical Activity Questionnaire; The Physical Self Perception Profile (PSPP);

260

Vancampfort et al., 2014 [269]

Belgium

100

 

Outpatient (adult, both sexes)

To compare the mental and physical health related QOL of 40 obese persons with BED with 20 age, gender and BMI matched obese persons without BED and 40 age and gender matched non-obese volunteers

Cross-sectional

Mental and physical health-related quality of life (HRQL)

261

Vaz, Conceicao and Machado, 2013 [270]

Portugal

42

 

Mixed (mixed cohort, both sexes)

To test the effectiveness of a cognitive-behavioural guided self-help treatment program for BN and similar disorders

Repeated measures (with follow up)

Eating Disorder Examination questionnaire (EDE-Q) score; Outcome-Questionnaire (OQ-45) score and Back Depression Inventory (BDI) score

262

Vaz, Conceição and Machado, 2014 [271]

Portugal

42

 

Outpatient (adult, females)

To investigate the sessions/time required for a clinical change with a guided self-help CBT treatment, to assess the predictive value of early response and other potential predictors of end-of-treatment clinical status

Case study

Structured Clinical Interview for DSM-IV (SCID), Eating Disorders Examination (EDE), Eating Disorders Examination Questionnaire (EDE-Q), Outcome Questionnaire (OQ), Beck Depression Inventory (BDI)

263

Vella-Zarb et al., 2014 [272]

Canada

45

 

Mixed (mixed cohort, both sexes)

To build on current research by comparing Motivational Interviewing with psychoeducation, each as a prelude to self-help treatment for BE

RCT

Readiness to change and confidence in ability to control binge eating

264

Vocks et al., 2010 [273]

Worldwide

 

38

Mixed (mixed cohort, both sexes)

To compute and compare mean effects of various treatments for BED

Meta-analysis

Varied

265

Vogel, Singh and Accurso, 2021 [274]

USA

 

50

Community (adolescent, both sexes)

To summarize and critically analyse the current literature on the feasibility, acceptability, effectiveness, and efficacy of CBT and DBT for adolescent eating disorders, and then proposes areas of future research

Systematic review/meta-analysis (combined)

AN outcomes, BN outcomes, BED outcomes, transdiagnostic outcomes

266

von Brachel et al., 2014 [275]

Germany

179

 

Community (adult, females)

To identify predictors of dropout from a Web-based 6-session program to enhance motivation to change for women with AN, BN, or related subthreshold eating pathology

Quasi-experimental (intervention)

ED pathology measured by EDE-Q; Motivation to change using URICA; Depressive Mood using HSCL-25

267

Wade et al., 2021a [276]

Australia

120

 

Outpatient (adult, both sexes)

To identify latent classes of trajectory of change in BMI between the initial and thirteenth session of outpatient treatment for adult AN and identify the association with outcome

Repeated measures (without follow up)

Body weight, ED psychopathology (EDE)

268

Wade et al., 2021b [277]

Australia

98

 

Outpatient (young/adult, both sexes)

To compare the efficacy of two forms of CBT-ED for patients with a BMI of more than 17.5—CBT-T and an expanded (10-session) CBTm—and to conduct an exploratory investigation of moderators

RCT

Global eating psychopathology, clinical impairment, depression, anxiety and stress, remission and good outcome, body avoidance, body checking, motivation

269

Wagner et al., 2013 [278]

Austria

155

 

Mixed (mixed cohort, both sexes)

To evaluate in a RCT the long-term effectiveness of internet guided self-help compared with conventional guided bibliotherapy in females with BN

RCT

Frequency of binge eating, vomiting and fasting

270

Wagner et al., 2015 [279]

Austria

126

 

Mixed (mixed cohort, both sexes)

To determine predictors of good long-term outcome and drop-out, in order to identify patients for whom these interventions are most suitable

RCT

Depressive symptomatology using BDI; general psychopathology using SIAB-EX; eating disorder inventory (EDI-2); temperament and character using TSI-R

271

Wagner et al., 2016 [280]

Germany

139

 

Outpatient (adult, both sexes)

To examine the efficacy of an Internet-based cognitive-behavioral intervention and to examine the stability of treatment effects over 12 months

RCT

Binge eating episodes, Eating Disorder Examination–Questionnaire (EDE-Q), Beck Depression Inventory (BDI), Symptom Checklist-90-Revised (SCL-90-R), body weight and BMI

272

Walker and Bryant, 2013 [281]

N/A

 

27

N/A

To synthesize findings from studies of the belief that people who have endured and overcome a psychiatric disability can offer useful support, encouragement, and hope to their peers

Review (other)

Varied

273

Waller et al., 2014 [282]

UK

78

 

Outpatient (adult, females)

To examine whether the efficacy of CBT for bulimic disorders can be translated into routine clinical practice

Case series

Eating behaviours and attitudes, depression pre- and post-treatment, frequency of bingeing and vomiting

274

Watson et al., 2011 [283]

Australia

353

 

Outpatient (adult, females)

To replicate the model in a sample of women with EDs and to investigate its predictive ability on binge eating and purging

Cross-sectional

Eating Disorder Examination (EDE), Weight Concern and Shape Concern subscales of the EDE (EDE-WSC), Self-Oriented Perfectionism subscale from the Eating Disorder Inventory-2 (EDI-SOP), Rosenberg Self-Esteem Scale (RSES)

275

Watson et al., 2017 [284]

USA

191

 

Outpatient (adult, both sexes)

To identify predictors and moderators of failure to engage and dropout in both Internet-based and traditional face-to-face CBT for BN

RCT

Failure to engage and drop-out rate

276

Watson et al., 2018 [285]

USA

179

 

Outpatient (adult, both sexes)

To evaluate the cost-effectiveness of Internet-based CBT for BN (CBT-BN) compared to face-to-face delivery of CBT-BN

RCT

Abstinence from binge-eating and purging; the mean cost per abstinence patient

277

Watson, Fursland and Byrne, 2013 [9]

Australia

972

 

Outpatient (adult, both sexes)

To describe the prevalence and characteristics associated with early exit at an outpatient ED service

Longitudinal (< 5 years)

Pathology of early exit group compared with non-early exit

278

Wilson and Zandberg, 2012 [286]

USA

 

136

Outpatient (adult, both sexes)

To determine the effectiveness and scalability of cognitive-behavioural guided self help for EDs

Review (narrative)

Varied

279

Wonderlich et al., 2014 [287]

USA

80

 

Outpatient (adult, both sexes)

To compare a new psychotherapy for BN, integrative cognitive-affective therapy, with an established treatment, CBT-E

RCT

Bulimic symptoms using generalised estimating equations (GEEs)

280

Zerwas et al., 2017 [288]

USA

179

 

Outpatient (adult, both sexes)

To compare an Internet-based manualized version of CBT group therapy for BN via a therapeutic chat group to the same treatment via a traditional face-to-face group therapy

RCT

Frequency of binge-eating and purging

281

Zipfel et al., 2014 [289]

Germany

242

 

Outpatient (adult, both sexes)

To assess the efficacy and safety of focal psychodynamic therapy and CBT-E versus optimised TAU

RCT

Weight gain, measured as increased body-mass index (BMI) at the end of treatment