Neural effects of deep brain stimulation on reward and loss anticipation and food viewing in anorexia nervosa: a pilot study

Table 2 Significant interaction effects for reward anticipation, pre- and post-DBS are compared for AN versus HC

Anatomical region	Time point	Effect ↑ increase ↓ decrease	Cluster size	MNI-coordinates			Statistics
Anatomical region	Time point	Effect ↑ increase ↓ decrease	Cluster size	x	y	z	Z-score	p-value
Precuneus R	Post-DBS	AN ↓	132	16	− 44	60	3.99	0.035
Putamen R	Post-DBS	AN ↓	169	26	− 10	16	4.69	0.025
VS R	Post-DBS	AN ↓	N/A	8	0	− 6	3.64	0.030*
mOFC	Post-DBS	AN ↑	N/A	− 2	32	− 22	3.55	0.043*

The direction of the effect is illustrated by an increase or decrease for the AN group post-DBS
*p-value after small volume correction (SVC)

ISSN: 2050-2974