The efficacy of non-invasive brain stimulation in the treatment of children and adolescents with Anorexia Nervosa: study protocol of a randomized, double blind, placebo-controlled trial

Table 1. Outcome measures.

Primary outcome measure	Secondary outcome measures
EDRC score (EDI-3)	Psychopatological	IC, IPC, APC, OC, GPMC scores (EDI-3) EAT-26 total score BUT-GSI CBCL 6–18 subscale’s t-scores YSR 11–18 subscale’s t-scores MASC-2 subscale’s t-scores CDI-2 subscale’s t-scores
	Neuropsysiological	TEPs, SICI/ICF and SAI protocols MEP amplitude in iTBS protocol
	Physiological	CAR, CAR AUCg and AUCi Nutritional state and BMI

APC Affective problems, BMI Body Mass Index, BUT Body Uneasiness Test, CBCL 6–18 Child behavior checklist for ages 6–18, CDI-2 Children’s depression inventory—second edition, AUCg Cortisol area under the curve relative to the ground, AUCi Cortisol area under the curve with respect to the increase, CAR Cortisol awakening response, EAT-26 Eating Attitudes Test, EDI-3 Eating Disorder Inventory, EDRC Eating Disorder Risk, GPMC General Psychological Maladjustment, GSI global severity index, IC Ineffectiveness, IPC Interpersonal problems, MEPs Motor-Evoked Potentials, MASC-2 Multidimensional Anxiety Scale For Children—second edition, OC Overcontrol, SICI/ICF Short intracortical inhibition and facilitation, SAI Short-latency afferent inhibition, iTBS Theta burst stimulation, TEPs TMS-evoked potentials, YSR 11–18 Youth Self-Report for Ages 11–18.

ISSN: 2050-2974