Fig. 3

Choice-related engagement in regions of interest before and after treatment and relationship with eating behavior. a Values extracted from the parametric choice analysis in our a priori anatomical ROI in the right anterior caudate (top panel). Choice-related activation in the caudate differed significantly between HC and AN at Time 1, but not at Time 2 (middle panel). Change in activity in the caudate from Time 1 to Time 2 was significantly correlated with the change in proportion high-fat food choices on the food choice task among individuals with AN, but not HC. Robust regression was used due to the presence of outliers. b Same analyses as in a for the a priori VMPFC ROI (MNI = [3 51 3]; top panel). c Same analyses as in a for the a priori DLPFC ROI (MNI = [− 48 15 24]; top panel). d For illustration purposes the same analyses as in a are presented for the parietal region identified in exploratory whole-brain analyses