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Table 6 Neural responses to body shape stimuli in people with AN

From: Physiological, emotional and neural responses to visual stimuli in eating disorders: a review

Author

AN Participants

HC participants

Stimuli

AN > HC

AN < HC

Seeger et al. 2002 [66]

3

3

Distorted image of self > distorted image of other > abstract colour image

R amygdala, brainstem, R gyrus fusiformis

n/a

Wagner et al. 2003 [67]

15

11

Distorted image of self > distorted image of other > abstract colour image

DLPFC and intraparietal sulcus

n/a

Uher et al. 2005 [68]

13

18

Line drawing of body shape > line drawing of houses

n/a

R parietal, R and lateral fusiform gyrus

Sachdev et al. 2008 [69]

10

10

Images of self > grey screen

n/a

Insula, PFC and occipital lobe

Image of other > grey screen

MPFC

n/a

Miyake et al. 2010 [64]

24 total

12 restrictive

12 binge purge subtype

12

Negative body image words > neutral words

Negative emotional words > neutral words

Amygdala, L MPFC, DLPFC and LI parietal

n/a

Vocks et al. 2010 [65]

13

27

Self-image

n/a

LI parietal lobe, M temporal gyrus, L uncus, parahippocampal

Image of other

R amygdala, bilateral para hippocampal, L uncus, L hippocampus, R posterior cingulate

n/a

Miyake et al. 2010 [53]

22

11

Distorted own body image

Amygdala, MPFC, DLPFC

n/a

Distorted image of other

R amygdala

Castellini et al. 2013 [52]

18

19

Own body image normal > distorted

frontal gyrus, M temporal gyrus, DLPFC

n/a

  1. R right, L left, DLPFC dorsolateral prefrontal cortex, OFC orbitofrontal cortex, ACC anterior cingulate cortex, M medial, S superior, I inferior