A preliminary exploration of the effect of concurrent antidepressant medication on responses to high-frequency repetitive transcranial magnetic stimulation (rTMS) in severe, enduring anorexia nervosa

Table 1 Baseline demographics and clinical characteristics for the antidepressant and no antidepressants groups

	Antidepressants (n = 16)	No antidepressants (n = 10)	Group comparison
Age (years) (mean ± SD)	29.56 ± 9.15	33.20 ± 13.29	U = 64.5, z = 0.82, p = 0.413
Illness duration (years) (mean ± SD)	14.16 ± 9.38	19.40 ± 14.13	U = 61.5, z = 0.98, p = 0.328
AN-R / AN-BP (n)	10 / 6	6 / 4	χ²(1) = 0.02, p = 0.899
BMI (kg/m²) (mean ± SD)	16.36 ± 1.50	15.95 ± 1.85	t(24) = −0.62, p = 0.540
EDE-Q Global (mean ± SD)	4.31 ± 0.82	3.64 ± 1.58	t(24) = − 1.45, p = 0.164
EDE-Q Restraint (mean ± SD)	4.20 ± 1.34	3.42 ± 1.86	t(24) = − 1.25, p = 0.225
EDE-Q Eating Concern (mean ± SD)	3.69 ± 0.80	3.28 ± 1.88	t(24) = − 0.77, p = 0.449
EDE-Q Shape Concern (mean ± SD)	4.83 ± 1.02	4.08 ± 1.68	U = 59, z = − 1.11, p = 0.266
EDE-Q Weight Concern (mean ± SD)	4.53 ± 0.98	3.78 ± 1.64	t(24) = − 1.46, p = 0.157
DASS-21 Total (mean ± SD)	74.00 ± 24.61	62.60 ± 29.33	t(24) = − 1.07, p = 0.296
DASS-21 Depression (mean ± SD)	29.13 ± 9.72	22.00 ± 10.71	t(24) = − 1.75, p = 0.093
DASS-21 Anxiety (mean ± SD)	17.38 ± 10.22	12.60 ± 10.96	t(24) = − 1.13, p = 0.865

Abbreviations: SD Standard deviation, AN-R Anorexia nervosa restricting type, AN-BP Anorexia nervosa binge-eating/purging type, n Number, BMI Body mass index, EDE-Q Eating Disorder Examination – Questionnaire, DASS-21 Depression, Anxiety and Stress Scales – Version 21

ISSN: 2050-2974