Low Calorie (n = 21) | High Calorie (n = 66) | ||||||
---|---|---|---|---|---|---|---|
Mean (S.D.) | Min | Max | Mean (S.D.) | Min | Max | P-value | |
Temperature | 36.4 (0.8) | 35.0 | 39.0 | 36.2 (0.5) | 35.0 | 37.0 | 0.17 |
Orthostatic Vital Signs: | |||||||
Lying Systolic Blood Pressure | 107 (12) | 89 | 135 | 104 (12) | 83 | 137 | 0.24 |
Lying Diastolic Blood Pressure | 67 (11) | 49 | 88 | 61 (9) | 80 | 63 | 0.03 |
Lying Heart Rate (bpm) | 64 (24.5) | 40 | 121 | 57 (17) | 31 | 116 | 0.18 |
Standing Systolic Blood Pressure | 104 (13.3) | 88 | 131 | 101 (11) | 72 | 128 | 0.45 |
Standing Diastolic Blood Pressure | 67 (9.5) | 49 | 83 | 64 (12) | 40 | 103 | 0.88 |
Standing Heart Rate (bpm) | 71 (25.5) | 39 | 125 | 73 (21) | 42 | 113 | 0.75 |
Labs: | |||||||
Sodium (mmol/L) | 140.4 (3.8) | 134.0 | 148.0 | 141.1 (3.3) | 131.0 | 147.0 | 0.20 |
Potassium (mmol/L) | 3.8 (0.9) | 3.0 | 7.0 | 3.6 (0.6) | 3.0 | 5.0 | 0.27 |
Chloride (mmol/L) | 102.7 (4.3) | 95.0 | 113.0 | 102.0 (2.9) | 92.0 | 111.0 | 0.80 |
Bicarb (mmol/L) | 26.6 (3.6) | 18.0 | 32.0 | 27.5 (2.6) | 20.0 | 33.0 | 0.23 |
BUN (mg/dl) | 13.2 (7.2) | 2.0 | 31.0 | 15.8 (6.9) | 1.0 | 37.0 | 0.14 |
Creatinine (mg/dL) | 0.1 (0.03) | 0.00 | 1.0 | 0.03 (0.17) | 0.0 | 1.0 | 0.21 |
Glucose (mg/dL | 87.1 (30.4) | 54.0 | 180.0 | 83.0 (17.1) | 31.0 | 142.0 | 0.45 |
Phosphorus (mg/dL) | 3.7 (0.6) | 2.0 | 4.0 | 3.8 (0.7) | 1.0 | 5.0 | 0.72 |
Magnesium (mg/dL) | 1.7 (0.5) | 1.0 | 2.0 | 1.89 (0.3) | 1.0 | 2.0 | 0.07 |
AST (U/L) | 34.1 (13.4) | 10.2 | 76.0 | 35.4 (12.0) | 10.0 | 74.0 | 0.69 |
ALT (U/L) | 38.3 (15.5) | 15.0 | 66.0 | 31.9 (12.3) | 14.0 | 98.0 | 0.05 |
Prealbumin (mg/dL) | 19.1 (6.2) | 10.0 | 30.0 | 20.9 (4.2) | 11.0 | 32.0 | 0.15 |
Vitamin D (ng/mL) | 35.6 (7.7) | 23.0 | 44.0 | 37.8 (13.5) | 15.0 | 79.0 | 0.66 |
WBC (thousand/uL) | 5.8 (1.6) | 3.5 | 11.0 | 5.4 (1.4) | 1.6 | 9.7 | 0.26 |
Hgb (g/dL) | 12.7 (1.2) | 11.0 | 14.0 | 12.9 (1.3) | 8.7 | 16.0 | 0.54 |
CRP (mg/dL) | 0.7 (0.4) | 0.5 | 2.2 | 0.60 (0.26) | 0.5 | 1.9 | 0.30 |
Estradiol (pg/mL) | 7.8 (7.7) | 2.0 | 24.0 | 13.4 (15.3) | 1.0 | 65.0 | 0.17 |
Testosterone (ng/mL) | 8.0 (5.3) | 2.0 | 12.0 | 24.5 (23.2) | 1.4 | 74.0 | 0.25 |
ECG: | |||||||
QTc (ms) | 0.410 (.031) | 0.346 | 0.457 | 0.408 (.026) | 0.335 | 0.470 | 0.81 |
Cardiac Monitoring: | |||||||
Lowest HR overnight – Admit (bpm) | 49.4 (14.1) | 29.0 | 78.0 | 43.8 (10.1) | 31.0 | 79.0 | 0.05 |
Lowest HR overnight – Discharge (bpm) | 68.8 (18.7) | 45.0 | 105.0 | 54.7 (9.5) | 42.0 | 79.0 | <0.001 |
Change in HR | 18.9 (16.0) | −10.0 | 49.0 | 10.5 (7.6) | −21.0 | 31.0 | <0.01 |
Frequency (%) | Frequency (%) | ||||||
Hypophosphatemiaa | 57.1 | 51.5 | 0.65 | ||||
Hypomagnesemiaa | 52.4 | 51.5 | 0.94 | ||||
Hypokalemiaa | 19.1 | 4.6 | 0.03 |