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Systematic review and meta-analysis of preventive interventions for eating disorders


Eating disorders (EDs) are serious mental disorders which have significant physical and psychological impacts. The aim of this study is to determine whether ED prevention programs are effective across the age spectrum.


Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsychInfo, EMBASE, and Scopus) were searched for published randomised controlled trials (RCTs) designed for preventing ED. Included trials were classified as both broader prevention strategies (eg. universal) and more specific prevention program (eg. cognitive behavioural therapy (CBT)). Quantitative meta-analyses were conducted.


A total of 3790 titles were retrieved via the initial search strategy. Ninety-eight RCTs were included in the meta-analysis. Most of studies used self-report measurements of ED risk factors, and did not report final outcomes of cases of ED prevented. For universal prevention, media literacy (ML) interventions demonstrated a significant reduction in ED risk factors (e.g. weight and shape concern) at up to 30 months after interventions for both male and female adolescents. For selective prevention CBT (delivered by class or online) and ML interventions have significantly reduced bulimic symptoms at 3- to 8- month follow up (SMD -0.31, 95% CI: -0.58 to -0.03), and thin-ideal internalisation at 3-month follow up (SMD -1.79, 95% CI: -3.14 to -0.45) , respectively. CBT and cognitive dissonance (CD) interventions for indicated prevention showed strong evidence and substantial effect in reducing both ED risk factor and ED symptoms. A healthy weight program which was designed to prevent both ED and obesity as an indicated prevention intervention was found to significantly reduce ED risk factors and body mass.


The study supported the conclusions that indicated prevention interventions using CBT and CD approaches are effective for ED prevention while universal and selective prevention using media literacy and selective prevention using CBT are promising. Combined ED and obesity prevention interventions require further research.

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Correspondence to Long KD Le.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Le, L.K., Barendregt, J., Hay, P. et al. Systematic review and meta-analysis of preventive interventions for eating disorders. J Eat Disord 3 (Suppl 1), O35 (2015).

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