Table 4 Results of the mixed model repeated measures analyses for assessments of eating disorder, major depressive, state-trait anxiety symptoms and quality of life using linear time weighted by the number of days between admission and 6-month follow-up

EDE-Q global score

Intercept

1.633

0.570

679

2.864

.004

0.514

2.752

Time 1 (ADM-FU)

1.374

0.130

679

10.558

 ≤ .001

1.118

1.630

Time 2 (DC-FU)

 − .0321

0.135

679

 − 2.385

.017

 − 0.585

 − 0.057

AN-BP

0.636

0.439

679

1.449

.148

 − 0.226

1.499

AN-R

0.474

0.446

679

1.062

.288

 − 0.402

1.350

BN

0.429

0.423

679

1.016

.310

 − 0.400

1.259

OSFED

0.589

0.416

679

1.417

.157

 − 0.227

1.406

Age at admission

 − 0.002

0.007

679

 − 0.280

.779

 − 0.015

0.011

Admit BMI

0.025

0.009

679

2.699

.007

0.007

0.043

Age of ED onset

 − 0.186

0.099

679

 − 1.880

.061

 − 0.380

0.089

LGBTQ

 − 0.199

0.147

679

 − 1.360

.174

 − 0.487

0.089

PTSD

1.063

0.324

679

3.284

 ≤ .001

0.427

1.698

PTSD × Time 1

0.001

0.003

679

0.224

.823

 − 0.005

0.006

PTSD × Time 2

 − 0.001

0.001

679

 − 1.225

.221

 − 0.004

0.001

EDI-2 total score

Intercept

35.556

16.366

667

2.173

.030

3.422

67.692

Time 1 (ADM-FU)

27.347

3.737

667

7.317

 ≤ .001

20.009

34.685

Time 2 (DC-FU)

 − 4.647

3.865

667

 − 1.202

.230

 − 12.236

2.943

AN-BP

22.728

12.613

667

1.802

.072

 − 2.037

47.494

AN-R

19.833

12.775

667

1.552

.121

 − 5.251

44.917

BN

17.547

12.092

667

1.451

.147

 − 6.196

41.290

OSFED

16.436

11.886

667

1.383

.167

 − 6.903

39.774

Age at admission

0.101

0.198

667

0.512

.609

 − 0.287

0.490

Admit BMI

0.872

0.268

667

3.251

 ≤ .001

0.345

1.398

Age of ED onset

 − 7.774

2.840

667

 − 2.737

.006

 − 13.351

 − 2.198

LGBTQ

 − 2.670

4.203

667

 − 0.635

.525

 − 10.924

5.583

PTSD

42.736

9.308

667

4.591

 ≤ .001

24.460

61.013

PTSD × time 1

 − 0.154

0.083

667

 − 1.846

.065

 − 0.318

0.010

PTSD × time 2

 − 0.025

0.033

667

 − 0.766

.444

 − 0.090

0.040

PHQ-9

Intercept

5.967

2.538

670

2.351

.019

0.984

10.949

Time 1 (ADM-FU)

5.081

0.578

670

8.788

 ≤ .001

3.946

6.216

Time 2 (DC-FU)

-2.629

0.599

670

 − 4.389

 ≤ .001

 − 3.806

 − 1.453

AN-BP

3.566

1.954

670

1.825

.069

 − 0.271

7.403

AN-R

3.399

1.980

670

1.717

.086

 − 0.488

7.286

BN

2.917

1.873

670

1.557

.120

 − 0.761

6.595

OSFED

3.519

1.841

670

1.911

.056

 − 0.096

7.134

Age at admission

 − 0.009

0.030

670

 − 0.304

.762

 − 0.069

0.051

Admit BMI

0.074

0.041

670

1.792

.074

 − 0.007

0.156

Age of ED onset

 − 0.918

0.439

670

 − 2.092

.037

 − 1.779

 − 0.056

LGBTQ

0.396

0.648

670

0.611

.541

 − 0.876

1.667

PTSD

5.404

1.434

670

3.768

 ≤ .001

2.588

8.220

PTSD × time 1

0.002

0.013

670

0.172

.863

 − 0.023

0.028

PTSD × time 2

 − 0.005

0.005

670

 − 0.969

.333

 − 0.015

0.005

STAI-state anxiety

Intercept

46.821

5.409

665

8.657

 ≤ .001

36.201

57.441

Time 1 (ADM-FU)

8.866

1.237

665

7.167

 ≤ .001

6.437

11.295

Time 2 (DC-FU)

 − 1.621

1.280

665

 − 1.266

.206

 − 4.135

0.893

AN-BP

1.340

4.166

665

0.322

.748

 − 6.840

9.520

AN-R

1.298

4.218

665

0.308

.758

 − 6.985

9.581

BN

0.288

3.992

665

0.072

.943

 − 7.551

8.127

OSFED

0.012

3.924

665

0.003

.998

 − 7.694

7.718

Age at admission

0.005

0.065

665

0.073

.942

 − 0.123

0.133

Admit BMI

0.096

0.089

665

1.084

.279

 − 0.078

0.270

Age of ED onset

 − 1.077

0.935

665

 − 1.152

.250

 − 2.913

0.759

LGBTQ

0.433

1.394

665

0.311

.756

 − 2.304

3.170

PTSD

9.445

3.073

665

3.073

.002

3.410

15.479

PTSD × time 1

 − 0.012

0.028

665

 − 0.433

.665

 − 0.066

0.042

PTSD × time 2

0.001

0.011

665

0.093

.926

 − 0.020

0.022

STAI-trait anxiety

Intercept

48.973

4.804

667

10.194

 ≤ .001

39.541

58.406

Time 1 (ADM-FU)

6.431

1.097

667

5.861

 ≤ .001

4.276

8.584

Time 2 (DC-FU)

 − 1.691

1.137

667

 − 1.487

.138

 − 3.924

0.542

AN-BP

2.252

3.700

667

0.609

.543

 − 5.014

9.518

AN-R

2.928

3.747

667

0.781

.435

 − 4.430

10.286

BN

1.968

3.546

667

.555

.579

 − 4.995

8.932

OSFED

1.0450

3.485

667

.300

.764

 − 5.799

7.889

Age at admission

 − 0.058

0.058

667

 − 1.003

.316

 − 0.171

0.055

Admit BMI

0.157

0.079

667

2.000

.046

0.003

0.311

Age of ED onset

 − 1.843

0.831

667

 − 2.220

.027

 − 3.474

 − 0.213

LGBTQ

1.056

1.233

667

.857

.392

 − 1.365

3.477

PTSD

10.827

2.723

667

3.977

 ≤ .001

5.481

16.173

PTSD × time 1

 − 0.004

0.024

667

 − .167

.867

 − 0.052

0.044

PTSD × time 2

 − 0.011

0.010

667

 − 1.181

.238

 − 0.030

0.008

EDQOL total score

Intercept

1.205

0.286

664

4.210

 ≤ .001

0.643

1.767

Time 1 (ADM-FU)

0.673

0.066

664

10.357

 ≤ .001

0.546

0.801

Time 2 (DC-FU)

0.038

0.067

664

0.568

.571

 − 0.094

0.170

AN-BP

0.0179

0.219

664

0.081

.935

 − 0.413

0.449

AN-R

 − 0.094

0.223

664

 − 0.421

.674

 − 0.531

0.343

BN

 − 0.065

0.210

664

 − 0.311

.756

 − 0.478

0.347

OSFED

 − 0.098

0.207

664

 − 0.474

.636

 − 0.504

0.308

Age at admission

 − 0.003

0.003

664

 − 0.952

.341

 − 0.010

0.003

Admit BMI

0.012

0.005

664

2.482

.013

0.002

0.021

Age of ED onset

 − 0.010

0.049

664

 − 2.007

.045

 − 0.196

 − 0.002

LGBTQ

0.011

0.073

664

0.147

.883

 − 0.132

0.153

PTSD

0.765

0.162

664

4.722

 ≤ .001

0.447

1.084

PTSD × time 1

 − 0.001

0.001

664

 − 0.813

.416

 − 0.004

0.002

PTSD × time 2

 − 0.001

0.001

664

 − 1.753

.080

 − 0.002

0.0001