From: Bone health in avoidant/restrictive food intake disorder: a narrative review
Authors | Study Design | Study Description | Sample Description | Sample Size | Endpoints | Results | ||
---|---|---|---|---|---|---|---|---|
HC | AN | ARFID | ||||||
Schorr et al. [27] | Cross-sectional | This study investigated the prevalence of low BMD, and its determinants, in men with AN, atypical AN, and ARFID | Sex: 100% Male Age: 18–63 Race: 100% White Location: Massachusetts General Hospital (Boston, MA) and Denver Health Medical Center (Denver, CO) | HC: N = 48 AN: N = 26 ARFID: N = 11 | Prevalence of PA spine BMD Z-score less than − 1 and − 2 | < − 1: 23% < − 2: 6% | < − 1: 77%a < − 2: 62%a | < − 1: 64% < − 2: 18% |
Prevalence of total hip BMD Z-score less than − 1 and − 2 | < − 1: 8% < − 2: 2% | < − 1: 50%a < − 2: 15% | < − 1: 64%a < − 2: 9% | |||||
Prevalence of femoral neck BMD Z-score less than − 1 and − 2 | < − 1: 10% < − 2: 2% | < − 1: 58%a < − 2: 23%a | < − 1: 45%a < − 2: 0% | |||||
Alberts et al. [23] | Cross-sectional retrospective case-note review | This study compared BMD between patients with ARFID vs. AN | Sex: 19% Male Age: 6–19 Race: 87% White Location: Great Ormond Street Hospital (London, Eng.) | AN: N = 118 ARFID: N = 16 | AN | ARFID | ||
Spine (L2-L4) BMD (mean, SD) | 0.92b, 0.17 | 0.70, 0.13 | ||||||
Spine (L2-L4) BMD Z-score (mean, SD) | − 1.43, 1.18 | -1.88, 0.91 | ||||||
Spine (L2-L4) BMAD Z-score (mean, SD) | − 1.03, 1.53 | -1.44, 0.88 |