From: Assessment and management of disorders of gut–brain interaction in patients with eating disorders
Term | Definition |
---|---|
Brain-Gut axis | Bidirectional neurohumoral communication between the gastrointestinal tract and central nervous system |
Brain-Gut behavior therapy | Evidence-based psychotherapeutic interventions that target brain-gut interaction, such as relaxation training, mindfulness training, cognitive behavioral therapy for GI disorders, and gut-directed hypnotherapy |
Complementary therapy | Natural products or mind–body medicine which are used in addition to or as an alternative to standard medical treatments |
Enteric nervous system | A complex network of nerves which line the GI tract and controls GI tract motility and function |
Manometry study | Study which measures pressures and patterns of GI organ motility and sensation |
Motility | Movement of contents through the GI tract, mediated by complex signaling between nerves and muscles |
Organic | In the context of DGBI, used to describe possible underlying anatomic (structural) or inflammation-related causes of symptoms (e.g. cancer, ulcer causing abdominal pain) |
Prokinetic | Pharmacological agents which promote movement of contents in the GI tract |
Neuromodulators | Pharmacological agents which primarily have activity in the noradrenergic, serotonergic, dopaminergic systems in the brain-gut axis |
Visceral hypersensitivity | A key pathophysiological mechanism involved in pain sensation in DGBI, causing heightened perception of gut stimuli |