Covariate | Total body BMD | Spine | Femur | Hip | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | L 95% CI | U 95% CI | p | β | L 95% CI | U 95% CI | p | β | L 95% CI | U 95% CI | p | β | L 95% CI | U 95% CI | p | |
All studies | ||||||||||||||||
Age | 0.08 |  − 0.15 | 0.32 | 0.485 | 0.27 | 0.00 | 0.55 | 0.050 | 0.19 |  − 0.30 | 0.69 | 0.443 |  |  |  |  |
Illness duration (yr) | 0.16 |  − 0.26 | 0.58 | 0.460 | 0.30 |  − 0.14 | 0.75 | 0.178 |  − 0.03 |  − 0.53 | 1.06 | 0.513 |  |  |  |  |
BMI (kg/m2) | 0.50 |  − 0.11 | 1.01 | 0.055 | 0.74 | 0.11 | 1.38 | 0.022 | 0.66 |  − 0.40 | 1.72 | 0.220 |  |  |  |  |
Fat mass (kg) | 0.24 | 0.09 | 0.39 | 0.002 | 0.26 | 0.04 | 0.48 | 0.022 | 0.07 |  − 0.21 | 0.35 | 0.632 |  |  |  |  |
Lean mass (kg) | 0.41 | 0.04 | 0.78 | 0.031 | 0.45 |  − 0.10 | 1.01 | 0.110 | 0.30 |  − 0.30 | 0.91 | 0.322 |  |  |  |  |
Amenorrhea (%) |  − 0.04 |  − 0.08 |  − 0.01 | 0.010 |  − 0.04 |  − 0.07 |  − 0.01 | 0.011 |  − 0.03 |  − 0.08 | 0.02 | 0.214 |  |  |  |  |
Amenorrhea duration (mo) | 0.03 |  − 0.03 | 0.09 | 0.380 | 0.04 |  − 0.04 | 0.11 | 0.347 |  − 0.99 |  − 2.15 | 0.17 | 0.095 |  |  |  |  |
OCP use (%) | 0.01 |  − 0.05 | 0.07 | 0.711 | 0.03 |  − 0.03 | 0.08 | 0.376 | 0.04 |  − 0.04 | 0.13 | 0.324 |  |  |  |  |
AN only | ||||||||||||||||
Age |  − 0.06 |  − 0.36 | 0.24 | 0.698 | 0.19 |  − 0.17 | 0.55 | 0.309 | 0.16 |  − 0.46 | 0.78 | 0.610 | 0.10 |  − 0.37 | 0.56 | 0.684 |
Illness duration (yr) |  |  |  |  |  |  |  |  |  |  |  |  | 0.15 |  − 1.03 | 1.34 | 0.804 |
BMI (Kg/m2) | 0.17 |  − 1.13 | 1.47 | 0.797 | 0.61 |  − 1.19 | 2.40 | 0.506 | 1.46 |  − 0.75 | 3.67 | 0.196 | 0.55 |  − 1.92 | 3.02 | 0.661 |
Fat mass (kg) | 0.32 | 0.05 | 0.60 | 0.021 | 0.22 |  − 0.19 | 0.64 | 0.291 |  − 0.07 |  − 0.50 | 0.37 | 0.768 |  − 0.24 |  − 0.85 | 0.38 | 0.445 |
Lean mass (kg) | 0.38 |  − 0.13 | 0.89 | 0.141 | 0.37 |  − 0.38 | 1.12 | 0.336 | 0.21 |  − 0.60 | 1.03 | 0.610 | 0.48 |  − 0.59 | 1.55 | 0.379 |
Amenorrhea (%) |  |  |  |  |  |  |  |  |  |  |  |  | 0.01 |  − 0.09 | 0.11 | 0.860 |
Amenorrhea duration (mo) |  − 0.17 |  − 0.46 | 0.12 | 0.250 |  |  |  |  |  |  |  |  |  − 0.07 |  − 0.50 | 0.36 | 0.747 |
OCP use (%) |  |  |  |  |  |  |  |  |  |  |  |  |  − 0.04 |  − 0.16 | 0.10 | 0.564 |