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Table 3 Meta-regression results of covariables effect on total, spine, femur and hip bone mineral density

From: Associations between bone mineral density, body composition and amenorrhoea in females with eating disorders: a systematic review and meta-analysis

Covariate

Total body BMD

Spine

Femur

Hip

β

L 95% CI

U 95% CI

p

β

L 95% CI

U 95% CI

p

β

L 95% CI

U 95% CI

p

β

L 95% CI

U 95% CI

p

All studies

Age

0.08

 − 0.15

0.32

0.485

0.27

0.00

0.55

0.050

0.19

 − 0.30

0.69

0.443

    

Illness duration (yr)

0.16

 − 0.26

0.58

0.460

0.30

 − 0.14

0.75

0.178

 − 0.03

 − 0.53

1.06

0.513

    

BMI (kg/m2)

0.50

 − 0.11

1.01

0.055

0.74

0.11

1.38

0.022

0.66

 − 0.40

1.72

0.220

    

Fat mass (kg)

0.24

0.09

0.39

0.002

0.26

0.04

0.48

0.022

0.07

 − 0.21

0.35

0.632

    

Lean mass (kg)

0.41

0.04

0.78

0.031

0.45

 − 0.10

1.01

0.110

0.30

 − 0.30

0.91

0.322

    

Amenorrhea (%)

 − 0.04

 − 0.08

 − 0.01

0.010

 − 0.04

 − 0.07

 − 0.01

0.011

 − 0.03

 − 0.08

0.02

0.214

    

Amenorrhea duration (mo)

0.03

 − 0.03

0.09

0.380

0.04

 − 0.04

0.11

0.347

 − 0.99

 − 2.15

0.17

0.095

    

OCP use (%)

0.01

 − 0.05

0.07

0.711

0.03

 − 0.03

0.08

0.376

0.04

 − 0.04

0.13

0.324

    

AN only

Age

 − 0.06

 − 0.36

0.24

0.698

0.19

 − 0.17

0.55

0.309

0.16

 − 0.46

0.78

0.610

0.10

 − 0.37

0.56

0.684

Illness duration (yr)

            

0.15

 − 1.03

1.34

0.804

BMI (Kg/m2)

0.17

 − 1.13

1.47

0.797

0.61

 − 1.19

2.40

0.506

1.46

 − 0.75

3.67

0.196

0.55

 − 1.92

3.02

0.661

Fat mass (kg)

0.32

0.05

0.60

0.021

0.22

 − 0.19

0.64

0.291

 − 0.07

 − 0.50

0.37

0.768

 − 0.24

 − 0.85

0.38

0.445

Lean mass (kg)

0.38

 − 0.13

0.89

0.141

0.37

 − 0.38

1.12

0.336

0.21

 − 0.60

1.03

0.610

0.48

 − 0.59

1.55

0.379

Amenorrhea (%)

            

0.01

 − 0.09

0.11

0.860

Amenorrhea duration (mo)

 − 0.17

 − 0.46

0.12

0.250

        

 − 0.07

 − 0.50

0.36

0.747

OCP use (%)

            

 − 0.04

 − 0.16

0.10

0.564

  1. P-value in bold indicates statistical significance (p < 0.05)
  2. BMD bone mineral density, β coefficient, L lower, U upper, CI confidence interval, p p-value, AN anorexia nervosa, yr years, mo months, OCP oral contraceptive pill