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Table 1 Inclusion and exclusion criteria for both study groups (with respect to ICD-10, DSM-V)

From: Expression of salivary immunoglobulins and their association with analgesic neuropeptide opiorphin in anorexia nervosa during adolescence

Criteria for Inclusion into the Study Group (AN)

Criteria for Inclusion into the Control Group

Criteria for Exclusion from Study and Control Groups

Female patients aged 12–18

Female patients aged 12–18

Children/adolescents with disorders of the central nervous system (e.g. epilepsy, serious injuries, and CNS infections)

Children/adolescents with diagnosed AN restrictive subtype as per ICD-10 and DSM-V diagnostic criteria (diagnosis confirmed by two independent psychiatrists)

Lack of mental disorders

Co-existing: schizophrenia, bipolar affective disorder, any serious somatic disorder

Clinically significant AN symptoms lasting over six months

No past or current ED symptoms

Chronic somatic diseases

BMI < 17 kg/m2

BMI 17–24 kg/m2

BMI > 25 kg/m2

Children/adolescents without hereditary mental disorders (first-degree relatives)

Children/adolescents without any hereditary mental disorder (first-degree relatives)

Persistent pharmacotherapy Hormonotherapy

Contraception

Pregnancy

Dietary supplements

Patient and parent or legal guardian approval

Patient and parent or legal guardian approval

Lack of acceptance from patients, parents, or legal guardians

  

Smoking

  

Professional scaling Orthodontic treatment Antibiotic therapy

Anti-inflammatory drugs 3 months before a dental examination

  1. AN anorexia nervosa, ED eating disorders, ICD-10 International Statistical Classification of Diseases and Related Health Problems (10th edition), DSM-V Diagnostic and Statistical Manual of Mental Disorders (5th ed.), CNS Central Nervous System; BMI Body Mass Index