Criteria for Inclusion into the Study Group (AN) | Criteria for Inclusion into the Control Group | Criteria for Exclusion from Study and Control Groups |
---|---|---|
Female patients aged 12–18 | Female patients aged 12–18 | Children/adolescents with disorders of the central nervous system (e.g. epilepsy, serious injuries, and CNS infections) |
Children/adolescents with diagnosed AN restrictive subtype as per ICD-10 and DSM-V diagnostic criteria (diagnosis confirmed by two independent psychiatrists) | Lack of mental disorders | Co-existing: schizophrenia, bipolar affective disorder, any serious somatic disorder |
Clinically significant AN symptoms lasting over six months | No past or current ED symptoms | Chronic somatic diseases |
BMI < 17 kg/m2 | BMI 17–24 kg/m2 | BMI > 25 kg/m2 |
Children/adolescents without hereditary mental disorders (first-degree relatives) | Children/adolescents without any hereditary mental disorder (first-degree relatives) | Persistent pharmacotherapy Hormonotherapy Contraception Pregnancy Dietary supplements |
Patient and parent or legal guardian approval | Patient and parent or legal guardian approval | Lack of acceptance from patients, parents, or legal guardians |
 |  | Smoking |
 |  | Professional scaling Orthodontic treatment Antibiotic therapy Anti-inflammatory drugs 3 months before a dental examination |