Serum and plasma levels of brain-derived neurotrophic factor in individuals with eating disorders (EDs): a systematic review and meta-analysis

Table 3 Meta − regression of BDNF levels in persons with EDs and healthy controls

Moderator	No. of comparisons	No. of subjects		Meta-regression				R² analog (proportion of variance explained)
Moderator	No. of comparisons	ED	HC	Estimated Intercept	95% CI		p-value	R² analog (proportion of variance explained)
No. of persons with EDs	14	722	466	− 1.2303	− 1.9597	− 0.5009	0.0331	24.56%
Age (mean, years)	14	722	466	0.6128	− 0.0624	1.2880	< 0.0001	84.39%
Publication year	14	722	466	− 1.6911	− 2.9995	− 0.3826	0.0013	46.99%
NOS score	14	NA	NA	− 1.1455	− 2.9337	0.6426	0.4344	0.00%
All moderators combined (Multiple Meta − Regression)	13	NA	NA	51.8716	− 157.1692	260.9124	0.1098	66.80%

ISSN: 2050-2974