Management of eating disorders for people with higher weight: clinical practice guideline

Table 3 Psychotropic medications commonly used in anorexia nervosa, bulimia nervosa and binge-eating disorder

Psychotropic	Medication/class	Indication	Main effects	Appetite impacts	Other and adverse effects
Antidepressant	SSRI	Bulimia nervosa; BED; Depression	Reduction binge eating Improved mood	Increase or decrease	Generally well-tolerated; may have longer term adverse effects (e.g., sexual dysfunction)
Anticonvulsant	Topiramate	Bulimia nervosa; BED	Reduction binge eating	Decrease	Sedation and neurological side effects
Antipsychotic	Second generation (e.g., quetiapine, olanzapine)	Anorexia nervosa	Reduction of anxiety & eating disorder ideation/preoccupation	Increase	Sedation and other adverse effects; appetite impacts when at an adequate weight
Psychostimulant	Lisdexamfetamine^a	BED	Reduction binge eating	Decrease	Risk of dependency^b; unclear when to withdraw^c

SSRI selective serotonin reuptake inhibitor
^aOnly Therapeutic Goods Administration (TGA) approved medication for use in eating disorders in Australia
^bLess than for other psychostimulants
^cLong-term impacts on appetite and weight after withdrawing are unknown

ISSN: 2050-2974