Effects of autism on 30-year outcome of anorexia nervosa

Table 7 Morgan-Russell subscale E5 (Employment record); dose–response analysis in the AN group

	Employment record																Analysis for time trend
	AN Study 2				AN Study 3				AN Study 4				AN Study 5				Doubly ordered R × C tables linear-by linear
Dose	Response category				Response category				Response category				Response category				Test statistic	Exact P
Dose	0	4	8	12	0	4	8	12	0	4	8	12	0	4	8	12
Never ASD	3	3	5	24	4	1	3	27	8	2	6	19	0	3	11	17	−0.5697	0.6
ASD × 1–3	3	1	0	6	0	1	4	5	5	1	0	4	2	2	3	3	−0.9551	0.4
ASD × 4	3	0	0	3	4	1	0	1	4	0	1	1	4	0	0	2	−0.528	0.6

Dose–response analysis	Doubly ordered R x C tables				Stratified R × contingency
Dose–response analysis	Linear-by-linear association test				Cochran–Mantel–Haenszel
Test statistic	−2	−3.22	−2.437	−3.39	Test statistic—5.427
Exact p	0.05	0.0015	0.014	0.0007	Exact p < 0.00001

AN: anorexia nervosa; R × C: rows and columns; AN study 2: 6-year follow-up; AN study 3: 10-year follow-up; AN study 4: 18-year follow-up; AN study 5: 30-year follow-up; ASD × 4: Individuals in the AN group with an ASD diagnosis at AN Study 1 to AN Study 4 (all four examinations) (n = 6); ASD × 1–3: those who had been assigned an ASD diagnosis at least once and at most three times (n = 10); never ASD: those who had never fulfilled criteria for ASD (n = 34)
Raw data are situated in the middle of the table. Results of the initial omnibus test, a stratified Cochran–Mantel–Haenszel test for a doubly ordered R × C table, are placed in the lower right corner. Results of the analyses for time trend, the Linear-by-Linear Association test, are placed to the right of each level of ‘dose’. Below each follow-up study we have placed the results of the ‘dose–response’ analyses, using the Linear-by-Linear Associations test

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