Effects of autism on 30-year outcome of anorexia nervosa

Table 3 Morgan-Russell scale C (Mental state); dose–response analysis in the AN group

	Mental state																Analysis for time trend
																	Doubly ordered R × C tables
																	Linear-by-Linear Association Test
Dose		AN Study 2			AN Study 3				AN Study 4				AN study 5				Test Statistic	exact p
	Response category				Response category				Response category				Response category
	0	4	8	12	0	4	8	12	0	4	8	12	0	4	8	12
Never ASD	0	4	12	18	0	5	9	20	0	6	8	20	0	7	9	14	−0.9656	0.35
ASD × 1–3	0	3	1	6	0	1	4	5	0	2	3	5	0	5	2	3	−1.326	0.2
ASD × 4	1	3	0	2	1	3	1	1	2	1	3	0	2	1	3	0	−0.6396	0.6

Dose–response analysis	Linear-by-linear association test				Stratified R × C contingency table
Doubly ordered R × C tables	Linear-by-linear association test				Cochran–Mantel–Haenszel test
Test statistic	−2.165	−2.562	−2.787	−2.695	Test statistic −5.119
Exact p	0.03	0.01	0.006	0.008	Exact p < 0.00001

AN: anorexia nervosa; R × C: rows and columns; AN study 2: 6-year follow-up; AN study 3: 10-year follow-up; AN study 4: 18-year follow-up; AN study 5: 30-year follow-up; ASD × 4: Individuals in the AN group with an ASD diagnosis at AN Study 1 to AN Study 4 (all four examinations) (n = 6); ASD × 1–3: those who had been assigned an ASD diagnosis at least once and at most three times (n = 10); never ASD: those who had never fulfilled criteria for ASD (n = 34)
Raw data are situated in the middle of the table. Results of the initial omnibus test, a stratified Cochran–Mantel–Haenszel test for a doubly ordered R × C table, are placed in the lower right corner. Results of the analyses for time trend, the Linear-by-Linear Association test, are placed to the right of each level of ‘dose’. Below each follow-up study we have placed the results of the ‘dose–response’ analyses, using the Linear-by-Linear Associations test

ISSN: 2050-2974