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Table 2 Concentrations of markers of oxidative and carbonyl stress in patients with anorexia nervosa and healthy controls

From: Oxidative status in plasma, urine and saliva of girls with anorexia nervosa and healthy controls: a cross-sectional study

  Plasma Urine Saliva
Markers AN CTRL pBonf AN CTRL pBonf AN CTRL pBonf
TBARS 5.74 (3.47–10.82) 3.88 (3.15–6.48) NS 1.60 (0.38–6.73) 1.16 (0.28–1.45) NS 0.48 (0.22–0.90) 0.11 (0.08–0.13) <0.0001
μmol/l   μmol/mmol creatinine   μmol/l  
AOPP 0.84 (0.54–1.26) 0.33 (0.23–0.84) <0.0001 48.4 (25.7–81.3) 12.0 (9.8–16.6) <0.0002 8.20 (2.8–23.4) 24.5 (6.1–34.9) NS
μmol/g proteins   μmol/mmol creatinine   μmol/l  
AGEs 0.030 (0.020–0.040) 0.023 (0.018–0.024) <0.0001 ND ND   0.47 (0.28–0.82 0.31 (0.16–0.43 <0.0071
g/g proteins   g/mmol creatinine   g/l  
FRUCTOS 1.85 (1.39–2.20) 1.36 (1.24–1.97) NS 0.72 (0.52–1.03) 0.48 (0.37–0.54) .<0.0083 0.21 (0.14–0.39) 0.09 (0.04–0.30) NS
mmol/l   mmol/mmol creatinine   mmol/l  
FRAP 592 ± 129 600 ± 153 NS 1555 (613–5309) 552 (395–819) <0.0002 131 (66–267) 143 (105–161) NS
μmol/l   μmol/mmol creatinine   μmol/l  
TAC 393 (235–674) 879 (502–1164) <0.0001 1652 (699–4533) 573 (481–958) <0.0002 567 (260–776) 393 (234–541) NS
μmol/l   μmol/mmol creatinine   μmol/l  
GSH/GSSG 5.46 (4.51–9.16) 8.99 (6.03–12.51) <0.0001 0.81 (0.70–1.14) 1.32 (0.78–1.54) NS 0.66 (0.38–1.42) 0.37 (0.30–0.43) <0.001
ratio   ratio   ratio  
  1. AGEs advanced glycation end products, AN anorexia nervosa, AOPP advanced oxidation protein products, FRAP ferric reducing antioxidant power, FRUCTOS fructosamines, GSH/GSSG a ratio of reduced and oxidized glutathione, NS non-significant, TAC total antioxidant capacity, TBARS thiobarbituric acid reactive substance; Results are expressed as mean ± SD (normally distributed data) or as median (interquartile range), (skewed data)