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Table 2 Concentrations of markers of oxidative and carbonyl stress in patients with anorexia nervosa and healthy controls

From: Oxidative status in plasma, urine and saliva of girls with anorexia nervosa and healthy controls: a cross-sectional study

 

Plasma

Urine

Saliva

Markers

AN

CTRL

pBonf

AN

CTRL

pBonf

AN

CTRL

pBonf

TBARS

5.74 (3.47–10.82)

3.88 (3.15–6.48)

NS

1.60 (0.38–6.73)

1.16 (0.28–1.45)

NS

0.48 (0.22–0.90)

0.11 (0.08–0.13)

<0.0001

μmol/l

 

μmol/mmol creatinine

 

μmol/l

 

AOPP

0.84 (0.54–1.26)

0.33 (0.23–0.84)

<0.0001

48.4 (25.7–81.3)

12.0 (9.8–16.6)

<0.0002

8.20 (2.8–23.4)

24.5 (6.1–34.9)

NS

μmol/g proteins

 

μmol/mmol creatinine

 

μmol/l

 

AGEs

0.030 (0.020–0.040)

0.023 (0.018–0.024)

<0.0001

ND

ND

 

0.47 (0.28–0.82

0.31 (0.16–0.43

<0.0071

g/g proteins

 

g/mmol creatinine

 

g/l

 

FRUCTOS

1.85 (1.39–2.20)

1.36 (1.24–1.97)

NS

0.72 (0.52–1.03)

0.48 (0.37–0.54)

.<0.0083

0.21 (0.14–0.39)

0.09 (0.04–0.30)

NS

mmol/l

 

mmol/mmol creatinine

 

mmol/l

 

FRAP

592 ± 129

600 ± 153

NS

1555 (613–5309)

552 (395–819)

<0.0002

131 (66–267)

143 (105–161)

NS

μmol/l

 

μmol/mmol creatinine

 

μmol/l

 

TAC

393 (235–674)

879 (502–1164)

<0.0001

1652 (699–4533)

573 (481–958)

<0.0002

567 (260–776)

393 (234–541)

NS

μmol/l

 

μmol/mmol creatinine

 

μmol/l

 

GSH/GSSG

5.46 (4.51–9.16)

8.99 (6.03–12.51)

<0.0001

0.81 (0.70–1.14)

1.32 (0.78–1.54)

NS

0.66 (0.38–1.42)

0.37 (0.30–0.43)

<0.001

ratio

 

ratio

 

ratio

 
  1. AGEs advanced glycation end products, AN anorexia nervosa, AOPP advanced oxidation protein products, FRAP ferric reducing antioxidant power, FRUCTOS fructosamines, GSH/GSSG a ratio of reduced and oxidized glutathione, NS non-significant, TAC total antioxidant capacity, TBARS thiobarbituric acid reactive substance; Results are expressed as mean ± SD (normally distributed data) or as median (interquartile range), (skewed data)