Certainty assessment | Impact | Certainty | Importance | ||||||
---|---|---|---|---|---|---|---|---|---|
№ of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | |||
Outcomes: BMI; Depression Anxiety and Stress Scale (DASS-21) | |||||||||
1 | randomised trial | not serious | not serious | not serious | not serious | none | 1 feasibility RCT with AN participants (n = 24 internet-MANTRA +treatment as usual; n = 17 treatment as usual) [79]. At 6 months: little difference between iMANTRA group (internet-based self-help workbook + email support by therapist for AN relapse prevention) and treatment as usual group. At 12 months: iMANTRA group had a higher BMI than treatment as usual group, but confidence intervals were wide and overlapped with 0. | ⨁⨁⨁⨁ HIGH | CRITICAL |
At 12 months, iMANTRA group had lower DASS-21 scores compared to treatment as usual group [79]. |