Eligibility criteria | |
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Study design | RCTs, prospective cohort studies, retrospective cohort studies, cross-sectional and case-control studies. |
Age | Children and adolescents < 18 y.o. Young adult 18–24 y.o. |
Gender | All gender |
Diagnosis | Meeting criteria for Anorexia Nervosa based on DSM-5, DSMIV-R or ICD-10 |
Severity of disease | Severe malnutrition (BMI < 16 kg/m2 (adult) or percent median BMI ≤70% or Z-score ≤ − 3 SD (adolescents)) OR Moderate malnutrition (BMI 16–16.99 kg/m2 (adult) or percent median BMI 70–79% or Z-score − 2 to − 2.9 SD (adolescents)) AND Acute medical instability at admission |
Admission | First and repeated admissions as long all episodes documented separately and other inclusion criteria are met |
Interventions | Defining at least one the following element of an inpatient admission protocol intended for AYAs with AN: -Refeeding plan -Laboratory surveillance -Cardio-respiratory stability monitoring -Supplementation |