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Table 4 Neural responses to food stimuli in people with BN

From: Physiological, emotional and neural responses to visual stimuli in eating disorders: a review

  BN participants HC participants Stimuli BN > HC BN < HC
Uher et al. 2004 [50] 10 19 Colour pictures of food > Non-food images
Emotional aversive > neutral images
ACC, MOFC L lateral and anterior parietal, LI parietal, L occipital, posterior cerebellum
Schienle et al. 2009 [56] 14 38 High calorie food images > disgust inducing images> neutral images Insula and ACC n/a
Brooks et al. 2011 [49] 8 24 Food > non-food DLPFC, postcentral gyrus, caudate, precentral gyrus, supplementary motor area bilateral superior temporal gyrus, bilateral insula, and visual cortex
Spangler et al. 2011 [59] 12 12 Computer generated thin and large body image
Scrambled image
Pregenual ACC n/a
Kim et al. 2012 [51] 20 20 High calorie food images > non-food images Anterior Insula, R middle frontal gyrus and cerebellum n/a
Skunde et al. 2016 [57] 28 29 Visual food stimuli > household item stimuli No differences seen No differences seen
  1. R right, L left, DLPFC dorsolateral prefrontal cortex, OFC orbitofrontal cortex, ACC anterior cingulate cortex, M medial, I inferior