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Table 2 The mean change scores (post-treatment and follow-up scores adjusted for baselinea) for the clinical outcome measures, including the number of participants (N), means, and standard deviations (SD) for the antidepressant and no antidepressant groups, and the estimated between-groups effect size (Cohen’s d with 95% confidence intervals)

From: A preliminary exploration of the effect of concurrent antidepressant medication on responses to high-frequency repetitive transcranial magnetic stimulation (rTMS) in severe, enduring anorexia nervosa

Measure

Antidepressants

No antidepressants

Between- subject d (95% CI)

N

Mean

SD

N

Mean

SD

Post-treatment (adjusted for baselinea)

 BMI

16

0.03

0.72

10

0.16

0.36

0.22 (− 0.58 to 1.01)

 EDE-Q Global

16

− 0.34

0.68

10

− 0.09

0.56

0.40 (−0.41 to 1.19)

 EDE-Q Restraint

16

−0.18

0.73

10

0.14

0.67

0.45 (−0.36 to 1.24)

 EDE-Q Eating Concern

16

−0.43

0.83

10

−0.12

0.84

0.37 (−0.43 to 1.16)

 EDE-Q Shape Concern

16

−0.45

0.74

10

−0.10

1.11

0.38 (−0.42 to 1.18)

 EDE-Q Weight Concern

16

−0.33

0.83

10

−0.30

0.94

0.03 (−0.76 to 0.82)

 DASS-21 Total

16

−9.00

22.14

10

−16.2

19.31

−0.34 (−1.13 to 0.46)

 DASS-21 Depression

16

−1.25

8.61

10

−4.80

8.34

−0.42 (−1.21 to 0.39)

 DASS-21 Anxiety

16

−3.63

8.86

10

−4.20

4.76

−0.08 (− 0.87 to 0.72)

Follow-up (adjusted for baselinea)

 BMI

15

0.27

1.17

10

0.06

0.89

−0.20 (−1.00 to 0.91)

 EDE-Q Global

15

−0.88

0.85

10

−0.03

0.62

1.10 (0.23 to 1.96)

 EDE-Q Restraint

15

−0.75

1.29

10

0.18

0.68

0.85 (0.001 to 1.67)

 EDE-Q Eating Concern

15

−0.67

1.06

10

0.06

0.95

0.71 (−0.12 to 1.53)

 EDE-Q Shape Concern

15

−1.06

0.83

10

−0.09

0.83

1.17 (0.29 to 2.03)

 EDE-Q Weight Concern

15

−1.04

1.01

10

−0.28

0.67

0.85 (0.006 to 1.68)

 DASS-21 Total

15

−17.33

23.80

10

−14.4

18.40

0.13 (−0.69 to 0.93)

 DASS-21 Depression

15

−8.13

10.43

10

−4.20

8.24

0.41 (−0.41 to 1.21)

 DASS-21 Anxiety

15

−4.40

7.57

10

−3.00

7.13

0.19 (−0.62 to 0.99)

  1. Abbreviations: N Number, SD Standard deviation, CI Confidence intervals, BMI Body mass index, EDE-Q Eating Disorder Examination – Questionnaire, DASS-21 Depression Anxiety and Stress Scales – Version 21
  2. aPost-treatment/follow-up scores minus baseline scores. Bold font signifies that the CI do not include 0