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Table 50 Bright light therapy during CBT-based inpatient treatment versus CBT-based inpatient treatment alone for children and adolescents with anorexia nervosa and major depressive disorder

From: Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Certainty assessment

Impact

Certainty

Importance

№ of studies

Study design

Risk of bias

Inconsistency

Indirectness

Imprecision

Other considerations

RCT - Change in Weight (assessed with: Change in BMI per week)

 1

randomised trials

serious a

not serious

not serious

serious b

none

One study randomized patients with AN-R and depressive symptoms (> 17 on HDRS) admitted to CBT-based inpatient treatment to receive either daily 30 min BLT + inpatient treatment (n = 12) ×  6 weeks or inpatient treatment only ×  6 weeks (n = 12). Patients in both groups had a significant change in their BMI during 6 week study, however change from baseline was statistically significant by week 3 (p = 0.038) in BLT group vs only significant change from baseline at week 6 (p = 0.048) in TAU group.

LOW

CRITICAL

  1. Explanations
  2. aNo blinding of subjects to treatment group
  3. bConfidence intervals overlapping with actual size of treatment effect
  4. Bibliography
  5. RCT - Janas-Kozik 2011 [242]