Table 42 CBT-based inpatient treatment for children and adolescents with anorexia nervosa
From: Canadian practice guidelines for the treatment of children and adolescents with eating disorders
Certainty assessment | Impact | Certainty | Importance | ||||||
|---|---|---|---|---|---|---|---|---|---|
№ of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | |||
Weight Change (assessed with: Pre-post weight measures), EDI-2 Scores pre and post | |||||||||
2 | Case Series | very serious a | not serious | not serious | serious b | none | Two studies - Total 295 patients. In all studies patients gained weight in hospital. Weight change reported differently across studies. One study reported BMI pre/post with BMI increasing from 14.83 (+/− 1.22) at admission to 17.34 (+/− 1.37) at discharge signifying an ES of 2.1. One study reported change in BMI % which rose from mean of 1.46 (+/− 2.41) at admission to 9.44 (+/− 6.68) at discharge. | ⨁◯◯◯ VERY LOW | CRITICAL |
very serious a | not serious | not serious | serious b | all plausible residual confounding would reduce the demonstrated effect | One study which included 238 patients, mean LOS 81.9 (+/− 31.9) days. Global score and all subscales of the EDI-2 showed significant improvements. The ES of the Global score was 0.8. For subscales the highest ES was found for Drive for Thinness with an ES of 1.1, and the lowest ES was for Maturity Fears with an ES of 0.3. Forty-five % showed “clinically significant” changes in EDI-2 Global Scores, 23.6% showed “reliable” changes, 28% of patients remained unchanged and 3.7% deteriorated. | ⨁◯◯◯ VERY LOW | IMPORTANT | ||
Weight | |||||||||
1 | Case Report | very serious a | not serious | not serious | serious b | none | In the case study weight increased 1.1 kg in 6 days. | ⨁◯◯◯ VERY LOW | CRITICAL |