Skip to main content

Table 33 SSRIs for children and adolescents with Bulimia Nervosa

From: Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Certainty assessment

Impact

Certainty

Importance

№ of studies

Study design

Risk of bias

Inconsistency

Indirectness

Imprecision

Other considerations

Binge Frequency (assessed with: average weekly binges), purge frequency, psychological symptoms, depression (BDI)

 1

Case Series

very serious a

not serious

not serious

not serious

none

Ten subjects all female, no control group. 8 week study of fluoxetine 60 mg/day. Binge frequency decreased from 4.1 to 3.8 (p < 0.01).

Purge frequency decreased from 6.4 to 5.2 (p < 0.005).

VERY LOW

CRITICAL

very serious a

not serious

not serious

not serious

none

EDI Bulimia Subscale decreased significantly from 10.6 to 4.2 (P < 0.01).

VERY LOW

CRITICAL

very serious a

not serious

not serious

not serious

none

BDI scores were not significantly different pre and post.

VERY LOW

CRITICAL

Adverse Effect - Mania

 1

Case Report

very serious a,b

not serious

not serious

not serious

none

Case described of teen with BN treated with fluoxetine 20 mg who developed mania - fluoxetine stopped and valproate started.

VERY LOW

CRITICAL

  1. Explanations
  2. ano control group
  3. Bibliography:
  4. Case Series - Kotler 2003 [173]
  5. Case report - Tor 2008 [174]