Table 3 Linear regression model of clinical characteristics (chronological age, BMI, Tanner status, duration of AN, amenorrhea, body fat mass and lean body mass) associated with the four bone mineral parameters (TB-BMD and LS-BMD, TB-BMC, TB-BMC/LBM)
From: Abnormal bone mineral density and content in girls with early-onset anorexia nervosa
TB BMC (SDS) | TB BMC/LBM (%) | TB BMD (SDS) | LS BMD (SDS) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
N=67 | N=67 | N=67 | N=67 | |||||||||
β | IC-95% | p-value | β | IC-95% | p-value | β | IC-95% | p-value | β | IC-95% | p-value | |
Chronological age (yrs) | 166.2 | [133.92; 198.49] | < 0.01 | 0.13 | [0.06; 0.20] | < 0.01 | 0.03 | [0.02; 0.04] | < 0.01 | 0.06 | [0.04; 0.07] | < 0.01 |
Pubertal stage | < 0.01 | 0.55 | 0.02 | < 0.01 | ||||||||
1 and 2 | ref. | ref. | ref. | ref. | ref. | ref. | ref. | ref. | ||||
3 to 5 | 217.25 | [71.32; 363.17] | 0.10 | [−0.24; 0.44] | 0.04 | [0.01; 0.08] | 0.09 | [0.04; 0.15] | ||||
BMI (SDS) | 15.45 | [−33.00; 63.90] | 0.53 | −0.13 | [− 0.24; − 0.02] | 0.07 | 0.01 | [0.00; 0.02] | 0.16 | 0.02 | [0.00; 0.04] | 0.02 |
FBM (kg) | −25.10 | [−66.67; 16.47] | 0.23 | 0.02 | [−0.07; 0.11] | 0.61 | 0.01 | [−0.01; 0.00] | 0.32 | −0.01 | [− 0.02; 0.01] | 0.45 |
LBM (kg) | 65.11 | [53.86; 76.35] | < 0.01 | 0.04 | [−0.01; 0.08] | 0.10 | 0.01 | [0.01; 0.01] | < 0.01 | 0.02 | [0.01; 0.02] | < 0.01 |
Disease duration (yrs) | −60.79 | [− 129.85; 8.27] | 0.08 | −0.03 | [− 0.19; 0.12] | 0.67 | − 0.01 | [− 0.02; 0.01] | 0.31 | −0.03 | [− 0.05; 0.00] | 0.06 |