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Table 3 Comparison patients with and without heart failure (defined by LVEF Fraction < 52% for male and 54% for female)

From: Echocardiographic abnormalities in 124 severely malnourished adult anorexia nervosa patients: frequency and relationship with body composition and biological features

 

Patients heart failure (n = 18)

Patients without heart failure(n = 107)

p

Age (Y)

28 ± 5

32 ± 3

NS

BMI (kg/m2)

11.4 ± 1.6

12.3 ± 2.5

NS

FFMI (kg)/weight2)

10.49 ± 1.0

10.18 ± 1.2

NS

FM (%)

9 ± 2

8.8 ± 4

NS

AN types:

 AN-R

7 (50%)

84 (76%)

NS

 AN-BP

7 (50%)

27 (24%)

0.16

Years of evolution of AN since AN diagnosis

11 ± 5

9 ± 7

NS

Selenium (mmol/l)

1 ± 0.1

1.4 ± 0.1

NS

Potassium (mmol/l)

4 ± 0.6

3.8 ± 0,6

NS

Calcium (mmol/l)

2 ± 0.2

2.2 ± 0.1

NS

Magnesium (mmol/l)

1 ± 0.2

0.8 ± 0.1

NS

BNP (pg/l)

60 ± 63

54 ± 63

NS

Albumin (g/l)

34 ± 9

37 ± 7

NS

Transthyretin (mg/l)

0.218 ± 0.096

0.248 ± 0.102

NS

CRP (mg/l)

5 ± 8

7 ± 23

NS

Hypertransaminasemia (% patients)

71%

43%

< 0.05

AST (UI)

290 ± 577.4

137.6 ± 425.8

ALT (UI)

280 ± 439.7

170.1 ± 371.4

HR (bpm)

70 ± 25

61 ± 17

NS

QT (ms)

402 ± 59

405 ± 54

NS

QTc (ms)

397 ± 30

388 ± 33

NS

QT/QTc

1.0 ± 0.1

1 ± 0.2

NS

  1. Data are expressed as mean + SD or number (percentage)
  2. p p-value, NS Not Significant, Y Years, BMI Body Mass Index, FFMI Free Fat Mass Indexed, FM Fat Mass, AN Anorexia Nervosa, AN-R Anorexia Nervosa Restrictive type, AN-BP Anorexia Nervosa Binge Eating/Purging type, BNP Brain Natriuretic Peptide, CRP C-Reactive Protein, AST Aspartate Transaminase, ALT Alanine Transaminase, HR Heart Rate, QTc corrected QT interval