|Authors & Journal||Participants||Mean Age (SD)||% Female||Procedure||Psychiatric / other exclusions||Findings|
1. Beato-Fernandez et al. (2011) |
Actas Espanolas de Psiqiuiatria, 39(4): 203-10.
No SD of mean age reported
|Not reported||3x SPECT scans to measure rCBF during rest condition; calm visual stimulus condition and another after seeing their own body (filmed).||Left handedness; psychiatric illness aside from ED; neurological disorders||
AN-R, AN-P, BN-P, BN-NP vs HCs: decreased right temporal rCBF when moving from rest condition to neutral visual image|
AN-R & BN-P vs other groups: increased right temporal rCBF going from neutral visual image to own body visual image
2. Karhunen et al. (2000) |
Psychiatry Research: Neuroimaging Section, 99: 29-42.
OB BED (n=8)|
OB non-BED (n=11)
OB BED: 36.1(9.3)|
OB non-BED: 45.0 (10.0)
|100%||1 x SPECT scan to measure rCBF while participants were looking at a control image (landscape) and 1 x SPECT scan while participants were looking at a portion of real food after an overnight fast.||
‘No other disorders or medication known to affect the variables examined’ (pp31)
OB BED vs OB non-BED & HCs: significantly greater increase in rCBF in the left hemisphere compared to the right hemisphere, particularly in the frontal and prefrontal cortices, in the food exposure condition|
All groups experienced a significant increase in hunger in the food exposure condition. In the OB-BED group only, this was associated with significantly higher rCBF in the left frontal and pre-frontal cortices
3. Delvenne et al. (1997) |
International Journal of Eating Disorders, 21(4):313-320.
BN: 26.2 (10.9)|
HCs: 25.7 (2.1)
|100%||Resting state PET with (18-F) fluorodeoxyglucose used to evaluate cerebral glucose metabolism.||History of electroconvulsive therapy (ECT); significant abnormalities on physical and neurological examination; left handedness; no psychoactive medication for a minimum of 10 days; history of neuroleptic medication||BN vs HCs: absolute hypometabolism of glucose both globally and regionally, notably in the parietal and superior frontal cortices. The BN group also showed a lower relative regional cerebral glucose metabolism in the parietal cortex|
4. Nozoe et al. (1995) |
Brain Research Bulletin, 36(3): 251-255.
BN: 21.0 (2.9)|
AN: 24.1 (7.8)
HCs: 20.3 (1.0)
|100%||Examined rCBF using SPECT before and after food intake (slice of cake)||Left handedness; abnormal neurological findings||
BN vs AN & HCs: highest rCBF before eating in the left temporal and bilateral inferior frontal regions. Also, BN showed less increase in cortical activity post-eating|
BN and AN showed opposite patterns of frontal reaction to food stimuli
AN: showed no marked cortical laterality or activation in any cortical area pre-eating but showed greater increased cortical activity post-eating