Table 2 Definitions of relapse, according to individual studies identified by the literature search
Authors | Criteria | Duration | Study quality |
|---|---|---|---|
Definitions of Relapse | |||
Isager et al., 1985 [33] | Loss of ≥15% of weight acquired during course of treatment (if resulting in weight ≤50 kg) | Any point in time within a 1 year period | Good |
Martin, 1985 [28] | If the patient required further psychiatric treatment after discharge during follow–up period | Not specified | Fair |
Norring and Sohlberg, 1993 [34] | “Ill” defined as having an eating disorder | Not specified | Good |
Eckert et al., 1995 [29] | Loss of ≥15% of average body weight (based on Metropolitan Height-Weight Chart, 1959), after achieving normal body weight | Any point after achieving normal weight during inpatient treatment or the follow up period | Good |
Strober et al., 1997 [4] | Full (“syndromal”) relapse: weight <85% of ideal body weight and recurrence of psychological symptoms Partial (“subsyndromal”) relapse: recurrence of psychological symptoms but ≥85% of ideal body weight | Not specified | Good |
Fichter and Quadflieg, 1999 [21] | Outcome “poor” defined using Morgan-Russell criteria | Not specified | Fair |
Pike 1998 [8] | BMI ≤ 18.5 or weight ≤85% of ideal body weight; a minimum 1 SD increase on the Eating Disorder Evaluation; loss of menstrual functioning if it has been previously normal; increase in restriction leading to weight loss; and possibly increased binge eating, compensatory behavior, or associated medical problems | Not specified | Fair |
Herzog, et al., 1999 [32] | Return to full criteria symptoms and/or Psychiatric Status Rating (PSR) score of 5 or 6 | 8 weeks following a state of full recovery | Good |
Lowe et al., 2001 [22] | Outcome “poor” defined using Morgan-Russell criteria and PSR score of 5 or 6 | Not specified | Good |
Kordy et al., 2002 [10] | Change from partial or full remission to full syndrome according to DSM-IV | Not specified | Good |
Carter, et al., 2004 [15] | BMI below 17.5 and/or at least one episode of binge eating/purging behavior per week | 3 consecutive months | Good |
Keel, et al., 2005 [17] | Return to full criteria symptoms and/or PSR score of 5 or 6 | Not specified | Good |
Walsh et al., 2006 [14] | BMI below 16.5 for 2 consecutive weeks, or severe medical complications, or risk of suicide, or development of another psychiatric disorder requiring treatment | 2 consecutive weeks (low BMI) | Good |
Eisler et al., 2007 [20] | Outcome “poor” defined using Morgan-Russell criteria | Not specified | Good |
Clausen, 2008 [18] | PSR score ≥3 | 3 months | Good |
Bodell and Mayer, 2011 [24] | Poor outcome, BMI ≤18.5 (using modified Morgan-Russell criteria) | Not specified | Fair |
Helverskov, et al., 2010 [16] | Return to full criteria symptoms and/or PSR score of 5 or 6 | Not specified | Good |
Carter et al., 2012 [7] | BMI < 17.5 or at least one episode of binge eating/purging behavior per week | 3 consecutive months | Good |
McFarlane et al., 2015 [31] | AN: BMI < 18.5 AN-BP: average 4 episodes of bingeing and/or vomiting per month, or BMI < 18.5 | 3 consecutive months | Good |