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Table 4 Comparison of Group A and Group B (blood biochemical findings on admission)

From: Risk factors for elevated liver enzymes during refeeding of severely malnourished patients with eating disorders: a retrospective cohort study

 

Group A

Group B

 

N = 32

N = 27

Median (IQR)

Range

Median (IQR)

Range

p valueb

TP (6.7–8.3 g/dL)a

7.1 (6.8–7.5)

5.2–8.3

6.6 (6.4–7.1)

5.9–7.9

0.034

Albumin (4–5 g/dL)

4.6 (3.9–4.9)

2.1–5.3

4.3 (3.7–4.7)

2.7–5.3

0.125

Glucose (70–109 mg/dL)

78 (71–92)

34–132

83 (71–93)

51–121

0.558

BUN (8–22 mg/dL)

14 (12–17)

6–34

13 (9–15)

6–39

0.138

Creatinine (0.4–0.7 mg/dL)

0.64 (0.60–0.70)

0.48–1.24

0.62 (0.54–0.71)

0.26–1.35

0.398

AST (13–33 IU/L)

20 (18–25)

13–63

25 (22–31)

18–56

0.004

LDH (119–229 IU/L)

189 (160–211)

146–272

196 (157–242)

129–370

0.659

ALP (115–359 IU/L)

179 (130–224)

74–514

195 (141–241)

24–758

0.518

GGT (10–47 IU/L)

14 (11–27)

8–109

19 (14–35)

8–120

0.198

WBC (3.8–8.5 × 103/μL)

4.5 (3.8–5.0)

2.4–6.6

3.8 (3.1–5.2)

2.1–9.6

0.161

RBC (3.6–5 × 106/μL)

4.1 (3.8–4.4)

2.6–5.4

3.9 (3.5–4.2)

3.1–5.5

0.128

Hemoglobin (11–16 g/dL)

12.3 (11.5–13.4)

8.1–16.4

11.9 (11.1–13.1)

9.4–16.1

0.349

Hematocrit (32–48%)

36.7 (35.0–40.1)

24.5–47.3

35.8 (33.1–38.6)

28.9–45.5

0.283

Platelets (160–410 × 103/μL)

216 (188–254)

154–396

207 (175–260)

150–490

0.732

  1. Patients in Group A had normal ALT levels (≤27 IU/L) during refeeding, while patients in Group B had elevated ALT levels (>27 IU/L) during refeeding
  2. ALT alanine aminotransferase, IQR interquartile range, TP total protein, BUN blood urea nitrogen, AST aspartate aminotransferase, LDH lactate dehydrogenase, ALP alkaline phosphatase, GGT gamma glutamyl transferase, WBC white blood cells, RBC red blood cells
  3. aReference range shown in parentheses. bMann-Whitney U test