Skip to main content

Table 3 Comparison of Group A and Group B (patients’ characteristics)

From: Risk factors for elevated liver enzymes during refeeding of severely malnourished patients with eating disorders: a retrospective cohort study

 

Group A

Group B

 

N = 32

N = 27

Median (IQR)

Range

Median (IQR)

Range

p valuea

Age (years)

19 (16–30)

11–46

30 (15–37)

10–54

0.322

Age of illness onset (years)

16 (15–18)

11–35

17 (13–21)

8–38

0.957

Duration of illness (years)

1.6 (0.8–12.5)

0.2–28.0

9.0 (1.0–16.0)

0.5–40.0

0.132

Duration of hospitalization (days)

46 (29–76)

15–138

48 (34–75)

23–154

0.568

BMI on admission (kg/m2)

12.2 (11.1–13.3)

9.2–14.3

12.3 (10.8–13.2)

8.1–14.9

0.831

BMI on discharge (kg/m2)

14.6 (13.6–15.0)

11.3–18.5

14.6 (13.9–16.1)

11.4–17.4

0.548

Ratio of BMI increasec

1.2 (1.1–1.3)

1.0–1.5

1.2 (1.1–1.3)

1.1–1.6

0.389

Speed of BMI increase ([kg/m2]/days)d

0.04 (0.03–0.05)

0.02–0.13

0.05 (0.03–0.07)

0.01–0.13

0.159

Minimum BMI during hospitalization (kg/m2)

12.0 (10.9–12.8)

9.2–14.0

12.2 (10.8–13.2)

8.1–14.4

0.749

Time to nadir BMI (days)

0 (0–1.8)

0–10.0

3.0 (0–6.0)

0–41.0

0.03

Initial prescribed calories (kcal/kg)

37.0 (29.7–47.2)

6.6–77.2

33.2 (27.4–48.2)

16.7–115.3

0.67

Maximum prescribed calories (kcal/kg)

71.8 (56.5–82.8)

47.1–113.1

67.2 (58.5–82.7)

43.0–116.5

0.927

Speed of caloric increase (kcal/days)e

36.6 (29.4–59.6)

0–98.3

33.3 (14.6–63.8)

0–595.0

0.721

 

Frequency (%)

p valueb

Early onset (<15 years old)

6 (33)

12 (67)

0.033

Peak or late onset (≥15 years old)

26 (63)

15 (37)

 
  1. Patients in Group A had normal ALT levels (≤27 IU/L) during refeeding, while patients in Group B had elevated ALT levels (>27 IU/L) during refeeding
  2. ALT alanine aminotransferase, IQR interquartile range, BMI body mass index, BW body weight
  3. cRatio of BMI increase: [BMI on discharge/BMI on admission]; dSpeed of BMI increase: [(BMI on discharge–BMI on admission)/duration of hospitalization]; eSpeed of caloric increase: [(maximum prescribed calories–initial prescribed calories)/days to maximum prescribed calories]; aMann-Whitney U test; bPearson chi-square test